Bronchiolitis Obliterans Organizing Pneumonia Associated with Systemic Lupus Erythematosus with Antiphospholipid Antibody

Fumio Otsuka, Tetsuki Amano, Naoko Hashimoto, Maki Takahashi, Nobuhiko Hayakawa, Hirofumi Makino, Zensuke Ota, Toshio Ogura

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Bronchiolitis obliterans organizing pneumonia (BOOP) is a pathologic entity characterized by the formation of fibrous tissue plugs within terminal bronchioles and alveolar ducts. Although BOOP has been associated with several connective tissue disorders, there are rare reports of BOOP in patients with systemic lupus erythematosus (SLE). We present a patient with SLE accompanying antiphospholipid antibody who developed recurrent respiratory symptoms and radiographic abnormalities. The diagnosis of BOOP was confirmed by transbronchial lung biopsy. This case suggests that not only SLE, but also the presence of antiphospholipid antibody, may be associated with the development of BOOP.

Original languageEnglish
Pages (from-to)341-344
Number of pages4
JournalInternal Medicine
Volume35
Issue number4
DOIs
Publication statusPublished - Jan 1 1996

Keywords

  • Antiphospholipid syndrome (APS)
  • Connective tissue disease
  • Interstitial pneumonia
  • Masson body
  • Transbronchial lung biopsy (TBLB)

ASJC Scopus subject areas

  • Internal Medicine

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