Brain-gut induction of heat shock protein (HSP) 70 mRNA by psychophysiological stress in rats

Shin Fukudo, Koji Abe, Michio Hongo, Atsushi Utsumi, Yasuto Itoyama

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

Restraint water-immersion stress-induced expression of heat shock protein (HSP)70 mRNA in the cerebral cortex and stomach of rats was evaluated by Northern blotting. Cerebral and gastric HSP70 mRNA significantly increased in the 6 h-stressed rats and the amount of mRNA measured as optical densities was highest in the 12 h-stressed rats. These data confirmed our previous observations and suggest that families of HSPs play a salient cytoprotective role in stress-vulnerable organs.

Original languageEnglish
Pages (from-to)146-148
Number of pages3
JournalBrain Research
Volume757
Issue number1
DOIs
Publication statusPublished - May 16 1997
Externally publishedYes

Keywords

  • Cerebral cortex
  • Heat shock protein (HSP)70
  • Messenger RNA
  • Northern blotting
  • Rat
  • Restraint water-immersion stress
  • Stomach

ASJC Scopus subject areas

  • Neuroscience(all)
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

Fingerprint Dive into the research topics of 'Brain-gut induction of heat shock protein (HSP) 70 mRNA by psychophysiological stress in rats'. Together they form a unique fingerprint.

  • Cite this