Bone marrow scintigraphy with 111In-chloride--a clinical value for the hematological diseases

M. Fujishima, Y. Hiraki, Y. Takeda, Y. Kohno, H. Niiya, K. Aono, S. Yorimitsu, I. Takahashi

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Abstract

Bone marrow scintigraphy with indium chloride (111In) was performed in fifty-one patients with the hematological diseases. The results of the investigation were that 1. in all patients, as well as in patients with aplastic anemia, no correlation was there between the degree of the indium chloride accumulation and peripheral blood counts, 2. in patients with aplastic anemia and pure red cell aplasia (PRCA) a tendency to reduction in uptake of indium chloride in bone marrow, 3. in patients with these two good correlation between the degree of indium chloride accumulation and histology of the erythroid bone marrow, but in patients with chronic myelocytic leukemia (CML) and atypical leukemia no correlation between the two, so it seemed unlikely that indium chloride should reflect the effective production of erythrocytes, 4. four patients with leukemia were studied with indium chloride bone marrow imaging two times to evaluate their responses to chemotherapy, and peripheral expansion was no change or reduced in two patients with acute myelocytic leukemia (AML) and one patient with acute lymphocytic leukemia (ALL) who obtained complete remission, but on the other hand, it enlarged in one patient with acute myelocytic leukemia who obtained partial remission, and 5. in two patients with chronic myelocytic leukemia it enlarged up to the ankle joints, which was considerably specific.

Original languageEnglish
Pages (from-to)552-557
Number of pages6
JournalRadioisotopes
Volume37
Issue number10
DOIs
Publication statusPublished - Oct 1988

ASJC Scopus subject areas

  • Radiation

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    Fujishima, M., Hiraki, Y., Takeda, Y., Kohno, Y., Niiya, H., Aono, K., Yorimitsu, S., & Takahashi, I. (1988). Bone marrow scintigraphy with 111In-chloride--a clinical value for the hematological diseases. Radioisotopes, 37(10), 552-557. https://doi.org/10.3769/radioisotopes.37.10_552