Blood compatibility and SOD activity of H2O2-oxidated titanium substrates

S. Takemoto, K. Tsuru, Satoshi Hayakawa, A. Osaka, S. Takashima

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Abstract

We examined blood compatibility and superoxide dismutase (SOD) activity of titania gels yielded on Ti substrate due to the treatment with H2O2 solutions. They were correlated to the titania gel surface characteristics. Ti subjected to the chemical treatment with H2O2(H2O2-Ti) had high blood compatibility or hardly coagulated, and showed higher SOD activity than Ti without the chemical treatment. Ti treated with a hydrogen peroxide containing TaCl5(H2O2/Ta-Ti) had little lower blood compatibility than H2O2-Ti, and the SOD activity for H2O2/Ta-Ti were lower than that for any other Ti (Ti, H2O2-Ti). Thus the decrease in SOD activity for the plasma contacted with H2O2/Ta-Ti was in part caused by the Ta ions on the titania gel.

Original languageEnglish
Pages (from-to)35-38
Number of pages4
JournalKey Engineering Materials
Volume192-195
Publication statusPublished - 2001

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ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Ceramics and Composites

Cite this

Takemoto, S., Tsuru, K., Hayakawa, S., Osaka, A., & Takashima, S. (2001). Blood compatibility and SOD activity of H2O2-oxidated titanium substrates. Key Engineering Materials, 192-195, 35-38.