Bismuth(III)-catalyzed dehydrative etherification and thioetherification of phenolic hydroxy groups

Masahito Murai, Kazuki Origuchi, Kazuhiko Takai

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Use of a bismuth catalyst allowed efficient dehydrative substitution of phenolic hydroxy groups with alcohols and thiols to form C-O and C-S bonds. The reaction required equimolar amounts of two readily available substrates that generated H2O as the only byproduct. The relatively mild reaction conditions were compatible with the functional groups selected, and provided excellent chemoselectivity.

Original languageEnglish
Pages (from-to)3828-3831
Number of pages4
JournalOrganic Letters
Volume16
Issue number14
DOIs
Publication statusPublished - Jul 18 2014

Fingerprint

Bismuth
Sulfhydryl Compounds
Functional groups
bismuth
Byproducts
Substitution reactions
Alcohols
Catalysts
Substrates
thiols
alcohols
substitutes
catalysts

ASJC Scopus subject areas

  • Organic Chemistry
  • Physical and Theoretical Chemistry
  • Biochemistry

Cite this

Bismuth(III)-catalyzed dehydrative etherification and thioetherification of phenolic hydroxy groups. / Murai, Masahito; Origuchi, Kazuki; Takai, Kazuhiko.

In: Organic Letters, Vol. 16, No. 14, 18.07.2014, p. 3828-3831.

Research output: Contribution to journalArticle

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