Biomimetics is an interdisciplinary scientific research focuses on making nature as a model of creative inspiration to study, analyze and design of new efficient engineering systems and modern technology. Smart materials are the foundation supporting the development of new biomimetic based technology. Wide range of biologically inspired robots and intelligent systems has been developed. However, engineering such biomimetic intelligent creatures were hampered by physical and technological constraints, and it is still a challenge. Making robots and intelligent creatures that are actuated by biologically inspired artificial muscles would create new reality with great potentials. This paper provides the concept of Biomimetic as an interdisciplinary field, discusses the enabling technologies, and presents the development of biologically inspired actuators.