Biogenous iron oxide-immobilized palladium catalyst for the solvent-free Suzuki-Miyaura coupling reaction

Kyoko Mandai, Toshinobu Korenaga, Tadashi Ema, Takashi Sakai, Mitsuaki Furutani, Hideki Hashimoto, Jun Takada

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Iron oxide produced by iron-oxidizing bacteria, Leptothrix ochracea, (biogenous iron oxide: BIO) was used as a support for immobilized palladium catalysts with organic cross-linkers. Palladium immobilized on BIO bearing imidazolium chloride delivered the desired biaryl products in sufficient yields in the Suzuki-Miyaura coupling reactions under solvent-free conditions and could be reused several times without significant loss of catalytic activity. It is shown that BIO can be exploited as a useful support for immobilization of palladium and the BIO-immobilized palladium catalyst effectively promotes the solvent-free Suzuki-Miyaura coupling reactions.

Original languageEnglish
Pages (from-to)329-332
Number of pages4
JournalTetrahedron Letters
Issue number3
Publication statusPublished - Jan 18 2012



  • Biogenous iron oxide
  • Immobilized catalyst
  • Palladium catalyst
  • Solvent-free reaction
  • Suzuki-Miyaura coupling reaction

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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