Abstract
The aim of this study was to determine the efficacy of intranasal desmopressin in the treatment of nocturnal polyuria in men with benign prostatic hyperplasia (BPH). Twelve men with BPH were treated with intranasal desmopressin at bedtime for nocturnal polyuria. All patients underwent video- urodynamic evaluation. The number of nocturia episodes was the dependent variable. Exclusion criteria included nephrolithiasis, active urinary tact infection, and history of myocardial infarction, congestive heart failure, and angina. Ten of 12 patients improved with the intranasal desmopressin therapy. Nocturia episodes decreased from a median of 3.6 ± 0.5 episodes/night before treatment to 1.8 ± 1.1 episodes/night 3 months after therapy (p = .01). The American Urological Association symptom index decreased from 19 ± 6 before treatment to 12 ± 6 after therapy (p = .02). Hyponatremia did not occur. We conclude that intranasal desmopressin is a promising therapy for nocturnal polyuria in selected BPH patients.
| Original language | English |
|---|---|
| Pages (from-to) | 191-194 |
| Number of pages | 4 |
| Journal | Techniques in Urology |
| Volume | 5 |
| Issue number | 4 |
| Publication status | Published - 1999 |
| Externally published | Yes |
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Keywords
- Benign prostate hyperplasia
- Bladder
- Desmopressin
- Urodynamics
- Vasopressin
ASJC Scopus subject areas
- Urology
Cite this
Beneficial effect of intranasal desmopressin for men with benign prostatic hyperplasia and nocturia : Preliminary results. / Chancellor, M. B.; Atan, A.; Rivas, D. A.; Watanabe, Toyohiko; Tai, H. L.; Kumon, H.
In: Techniques in Urology, Vol. 5, No. 4, 1999, p. 191-194.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Beneficial effect of intranasal desmopressin for men with benign prostatic hyperplasia and nocturia
T2 - Preliminary results
AU - Chancellor, M. B.
AU - Atan, A.
AU - Rivas, D. A.
AU - Watanabe, Toyohiko
AU - Tai, H. L.
AU - Kumon, H.
PY - 1999
Y1 - 1999
N2 - The aim of this study was to determine the efficacy of intranasal desmopressin in the treatment of nocturnal polyuria in men with benign prostatic hyperplasia (BPH). Twelve men with BPH were treated with intranasal desmopressin at bedtime for nocturnal polyuria. All patients underwent video- urodynamic evaluation. The number of nocturia episodes was the dependent variable. Exclusion criteria included nephrolithiasis, active urinary tact infection, and history of myocardial infarction, congestive heart failure, and angina. Ten of 12 patients improved with the intranasal desmopressin therapy. Nocturia episodes decreased from a median of 3.6 ± 0.5 episodes/night before treatment to 1.8 ± 1.1 episodes/night 3 months after therapy (p = .01). The American Urological Association symptom index decreased from 19 ± 6 before treatment to 12 ± 6 after therapy (p = .02). Hyponatremia did not occur. We conclude that intranasal desmopressin is a promising therapy for nocturnal polyuria in selected BPH patients.
AB - The aim of this study was to determine the efficacy of intranasal desmopressin in the treatment of nocturnal polyuria in men with benign prostatic hyperplasia (BPH). Twelve men with BPH were treated with intranasal desmopressin at bedtime for nocturnal polyuria. All patients underwent video- urodynamic evaluation. The number of nocturia episodes was the dependent variable. Exclusion criteria included nephrolithiasis, active urinary tact infection, and history of myocardial infarction, congestive heart failure, and angina. Ten of 12 patients improved with the intranasal desmopressin therapy. Nocturia episodes decreased from a median of 3.6 ± 0.5 episodes/night before treatment to 1.8 ± 1.1 episodes/night 3 months after therapy (p = .01). The American Urological Association symptom index decreased from 19 ± 6 before treatment to 12 ± 6 after therapy (p = .02). Hyponatremia did not occur. We conclude that intranasal desmopressin is a promising therapy for nocturnal polyuria in selected BPH patients.
KW - Benign prostate hyperplasia
KW - Bladder
KW - Desmopressin
KW - Urodynamics
KW - Vasopressin
UR - http://www.scopus.com/inward/record.url?scp=0032752419&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0032752419&partnerID=8YFLogxK
M3 - Article
C2 - 10591256
AN - SCOPUS:0032752419
VL - 5
SP - 191
EP - 194
JO - Techniques in Urology
JF - Techniques in Urology
SN - 1079-3259
IS - 4
ER -