Bax protein-like immunoreactivity in primary sensory and hypothalamic neurons of adult rats

Tomosada Sugimoto, Chun Xiao, Yi Fen He, Hiroyuki Ichikawa

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Bax protein-like immunoreactivity (Bax-ir) was examined in the perfusion-fixed, cryosectioned rat nervous system. In the central nervous system, hypothalamic neurons were the only neurons that exhibited Bax-ir in the cell body. Their axons traveled toward the median eminence, suggesting that the Bax-like immunoreactive (Bax-ir) hypothalamic neurons included neurosecretory ones. Bax-ir axons were observed in the solitary tract nucleus, and spinal and medullary dorsal hems. They appear to have been derived from Bax-ir primary sensory neurons in the viscerosensory nodose ganglion and somatosensory dorsal root and trigeminal ganglia. In the somatosensory ganglia, smaller cells exhibited stronger Bax-ir. Accordingly, the ir axons in the dorsal horn were most concentrated in lamina II.

Original languageEnglish
Pages (from-to)37-40
Number of pages4
JournalNeuroscience Letters
Volume215
Issue number1
DOIs
Publication statusPublished - Aug 30 1996

Fingerprint

bcl-2-Associated X Protein
Sensory Receptor Cells
Axons
Neurons
Substantia Gelatinosa
Nodose Ganglion
Trigeminal Ganglion
Median Eminence
Solitary Nucleus
Spinal Ganglia
Ganglia
Nervous System
Central Nervous System
Perfusion

Keywords

  • Bax
  • Dorsal horn
  • Hypothalamus
  • Parabrachial nucleus
  • Primary sensory neurons
  • Solitary tract nucleus

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Bax protein-like immunoreactivity in primary sensory and hypothalamic neurons of adult rats. / Sugimoto, Tomosada; Xiao, Chun; He, Yi Fen; Ichikawa, Hiroyuki.

In: Neuroscience Letters, Vol. 215, No. 1, 30.08.1996, p. 37-40.

Research output: Contribution to journalArticle

Sugimoto, Tomosada ; Xiao, Chun ; He, Yi Fen ; Ichikawa, Hiroyuki. / Bax protein-like immunoreactivity in primary sensory and hypothalamic neurons of adult rats. In: Neuroscience Letters. 1996 ; Vol. 215, No. 1. pp. 37-40.
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