Basic and important points regarding the diagnosis of oral cancers using fluorine-18-labeled fluoro-2-deoxy-d-glucose positron emission tomography–computed tomography: a review

Shinji Kito, Hirofumi Koga, Masafumi Oda, Tatsurou Tanaka, Masaaki Kodama, Manabu Habu, Ikuya Miyamoto, Shinya Kokuryo, Noriaki Yamamoto, Nao Wakasugi-Sato, Shinobu Matsumoto-Takeda, Daigo Yoshiga, Kenji Osawa, Shun Nishimura, Takaaki Joujima, Ken ichi Mochida, Noriaki Kawanabe, Kou Matsuo, Masataka Uehara, Masaaki SasaguriIzumi Yoshioka, Kazuhiro Tominaga, Yasuhiro Morimoto

Research output: Contribution to journalArticle

Abstract

Numerous studies, including our own, have revealed that positron emission tomography–computed tomography (PET/CT) using fluorine-18-labeled fluoro-2-deoxy-d-glucose (18F-FDG) is effective for the diagnosis of oral cancers. Large amounts of new information about primary tumors and metastatic lymph nodes have been acquired, and the use of 18F-FDG PET/CT has been shown to improve diagnostic precision in determining both the pathological characteristics of primary oral cancers and the presence of metastatic lymph nodes. However, substantial variations in 18F-FDG uptake in the oral and maxillofacial regions have been identified, and the differential diagnosis of some oral cancers and metastatic lymph nodes remains difficult for radiologists. Therefore, based on the previous research, the aim of the present study was to review the basic and important points regarding the diagnosis of primary oral cancers and metastatic lymph nodes using 18F-FDG PET/CT.

Original languageEnglish
Pages (from-to)1-8
Number of pages8
JournalOral Radiology
DOIs
Publication statusAccepted/In press - Mar 27 2017

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Keywords

  • Diagnosis
  • Fluorine-18-labeled fluoro-2-deoxy-d-glucose
  • Oral cancers
  • Oral cavity
  • Pitfall
  • Positron emission tomography–computed tomography

ASJC Scopus subject areas

  • Dentistry (miscellaneous)
  • Radiology Nuclear Medicine and imaging

Cite this

Kito, S., Koga, H., Oda, M., Tanaka, T., Kodama, M., Habu, M., Miyamoto, I., Kokuryo, S., Yamamoto, N., Wakasugi-Sato, N., Matsumoto-Takeda, S., Yoshiga, D., Osawa, K., Nishimura, S., Joujima, T., Mochida, K. I., Kawanabe, N., Matsuo, K., Uehara, M., ... Morimoto, Y. (Accepted/In press). Basic and important points regarding the diagnosis of oral cancers using fluorine-18-labeled fluoro-2-deoxy-d-glucose positron emission tomography–computed tomography: a review. Oral Radiology, 1-8. https://doi.org/10.1007/s11282-017-0273-0