The Baeyer-Villiger (B. V.) reaction using SeO2-H2O2 was examined for various benzaldehydes possessing methoxy groups and/or a furan ring. When benzaldehydes have an electron-donating group (methoxy group) at the ortho or para position to a formyl group, the B. V. reaction proceeded rapidly and in a good yield. Since the reaction using SeO2-H2O2 is carried out under a neutral condition, this reaction are applicable to aldehyde derivatives with a furan ring which is unstable against acid.
- Baeyer-Villiger reaction
- Selen dioxide-hydrogen peroxide
ASJC Scopus subject areas
- Pharmaceutical Science