Bacteria isolated from surgical infections and its susceptibilities to antimicrobial agents - Special references to bacteria isolated between April 2010 and March 2011

Nagao Shinagawa, Tsuyoshi Hoshikawa, Hideki Oshima, Naoki Aikawa, Junichi Sasaki, Masaru Suzuki, Kazuhiko Serine, Shinya Abe, Hiromitsu Takeyama, Takehiro Wakasugi, Keiji Mashita, Moritsugu Tanaka, Akira Mizuno, Masakazu Ishikawa, Akihiko Iwai, Takaaki Saito, Masayuki Muramoto, Shoji Kubo, Shigeru Lee, Kenichiro FukuharaMasaaki Taniguchi, Koichi Hirata, Tomohisa Furuhata, Tohru Mizuguchi, Hiroyuki Osanai, Yoshiyuki Yanai, Fumitake Hata, Chikasi Kihara, Kazuaki Sasaki, Keisuke Oono, Masashi Nakamura, Hitoshi Shibuya, Itaru Hasegawa, Masami Kimura, Kosho Watabe, Yasuhito Kobayashi, Hiroki Yamaue, Seiko Hirono, Yoshio Takesue, Toshiyoshi Fujiwara, Susumu Shinoura, Hideyuki Kimura, Hiromi Iwagaki, Naoyuki Tokunaga, Taijiro Sueda, Eiso Hiyama, Yoshiaki Murakami, Hiroki Ohge, Kenichiro Uemura, Hiroaki Tsumura, Tetsuya Kanehiro, Hitoshi Takeuchi, Kouji Tanakaya, Mitsuhiro Iwasaki

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Bacteria isolated from surgical infections during the period from April 2010 to March 2011 were investigated in a multicenter study in Japan, and the following results were obtained. In this series, 631 strains including 25 strains of Candida spp. were isolated from 170 (81.7%) of 208 patients with surgical infections. Four hundred and twenty two strains were isolated from primary infections, and 184 strains were isolated from surgical site infection. From primary infections, anaerobic Gram-negative bacteria were predominant, followed by aerobic Gram-negative bacteria, while from surgical site infection aerobic Gram-positive bacteria were predominant, followed by anaerobic Gram-negative bacteria. Among aerobic Gram-positive bacteria, the isolation rate of Enterococcus spp. such as Enterococcus faecalis, Enterococcus faecium, and Enterococcus avium was highest, followed by Streptococcus spp. such as Streptococcus anginosus and Staphylococcus spp. such as Staphylococcus aureus, in this order, from primary infections, while Enterococcus spp. such as E. faecalis and E. faecium was highest, followed by Staphylococcus spp. such as S. aureus from surgical site infection. Among aerobic Gram-negative bacteria, Escherichia coli was the most predominantly isolated from primary infections, followed by Klebsiella pneumoniae, Klebsiella oxytoca, Enterobacter cloacae, and Pseudomonas aeruginosa in this order, and from surgical site infection, E. coli and P. aeruginosa were most predominantly isolated, followed by E. cloacae and K. pneumoniae. Among anaerobic Gram-positive bacteria, the isolation rates of Parvimonas micro, Eggerthella lenta, Streptococcus constellatus, Gemella morbillorum, and Collinsella aerofaciens were the highest from primary infections, and the isolation rate from surgical site infection was generally low. Among anaerobic Gram-negative bacteria, the isolation rate of Bilophila wadsworthia was the highest from primary infections, followed by, Bacteroides fragilis and Bacteroides ovatus, and from surgical site infection, B.fragilis was most predominantly isolated, followed by Bacteroides thetaiotaomicron, in this order. In this series, vancomycin-resistant MRSA (methicillin-resistant S. aureus), vancomycin-resistant Enterococcus spp. and multidrug-resistant P. aeruginosa were not observed.

Original languageEnglish
Pages (from-to)293-334
Number of pages42
JournalJapanese Journal of Antibiotics
Volume67
Issue number5
Publication statusPublished - Oct 1 2014

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Anti-Infective Agents
Surgical Wound Infection
Bacteria
Gram-Negative Anaerobic Bacteria
Infection
Enterococcus
Gram-Positive Bacteria
Gram-Negative Aerobic Bacteria
Pseudomonas aeruginosa
Enterobacter cloacae
Enterococcus faecium
Aerobic Bacteria
Enterococcus faecalis
Klebsiella pneumoniae
Staphylococcus
Bilophila
Staphylococcus aureus
Streptococcus constellatus
Gemella
Streptococcus anginosus

ASJC Scopus subject areas

  • Pharmacology (medical)
  • Infectious Diseases
  • Microbiology (medical)
  • Medicine(all)

Cite this

Bacteria isolated from surgical infections and its susceptibilities to antimicrobial agents - Special references to bacteria isolated between April 2010 and March 2011. / Shinagawa, Nagao; Hoshikawa, Tsuyoshi; Oshima, Hideki; Aikawa, Naoki; Sasaki, Junichi; Suzuki, Masaru; Serine, Kazuhiko; Abe, Shinya; Takeyama, Hiromitsu; Wakasugi, Takehiro; Mashita, Keiji; Tanaka, Moritsugu; Mizuno, Akira; Ishikawa, Masakazu; Iwai, Akihiko; Saito, Takaaki; Muramoto, Masayuki; Kubo, Shoji; Lee, Shigeru; Fukuhara, Kenichiro; Taniguchi, Masaaki; Hirata, Koichi; Furuhata, Tomohisa; Mizuguchi, Tohru; Osanai, Hiroyuki; Yanai, Yoshiyuki; Hata, Fumitake; Kihara, Chikasi; Sasaki, Kazuaki; Oono, Keisuke; Nakamura, Masashi; Shibuya, Hitoshi; Hasegawa, Itaru; Kimura, Masami; Watabe, Kosho; Kobayashi, Yasuhito; Yamaue, Hiroki; Hirono, Seiko; Takesue, Yoshio; Fujiwara, Toshiyoshi; Shinoura, Susumu; Kimura, Hideyuki; Iwagaki, Hiromi; Tokunaga, Naoyuki; Sueda, Taijiro; Hiyama, Eiso; Murakami, Yoshiaki; Ohge, Hiroki; Uemura, Kenichiro; Tsumura, Hiroaki; Kanehiro, Tetsuya; Takeuchi, Hitoshi; Tanakaya, Kouji; Iwasaki, Mitsuhiro.

In: Japanese Journal of Antibiotics, Vol. 67, No. 5, 01.10.2014, p. 293-334.

Research output: Contribution to journalArticle

Shinagawa, N, Hoshikawa, T, Oshima, H, Aikawa, N, Sasaki, J, Suzuki, M, Serine, K, Abe, S, Takeyama, H, Wakasugi, T, Mashita, K, Tanaka, M, Mizuno, A, Ishikawa, M, Iwai, A, Saito, T, Muramoto, M, Kubo, S, Lee, S, Fukuhara, K, Taniguchi, M, Hirata, K, Furuhata, T, Mizuguchi, T, Osanai, H, Yanai, Y, Hata, F, Kihara, C, Sasaki, K, Oono, K, Nakamura, M, Shibuya, H, Hasegawa, I, Kimura, M, Watabe, K, Kobayashi, Y, Yamaue, H, Hirono, S, Takesue, Y, Fujiwara, T, Shinoura, S, Kimura, H, Iwagaki, H, Tokunaga, N, Sueda, T, Hiyama, E, Murakami, Y, Ohge, H, Uemura, K, Tsumura, H, Kanehiro, T, Takeuchi, H, Tanakaya, K & Iwasaki, M 2014, 'Bacteria isolated from surgical infections and its susceptibilities to antimicrobial agents - Special references to bacteria isolated between April 2010 and March 2011', Japanese Journal of Antibiotics, vol. 67, no. 5, pp. 293-334.
Shinagawa, Nagao ; Hoshikawa, Tsuyoshi ; Oshima, Hideki ; Aikawa, Naoki ; Sasaki, Junichi ; Suzuki, Masaru ; Serine, Kazuhiko ; Abe, Shinya ; Takeyama, Hiromitsu ; Wakasugi, Takehiro ; Mashita, Keiji ; Tanaka, Moritsugu ; Mizuno, Akira ; Ishikawa, Masakazu ; Iwai, Akihiko ; Saito, Takaaki ; Muramoto, Masayuki ; Kubo, Shoji ; Lee, Shigeru ; Fukuhara, Kenichiro ; Taniguchi, Masaaki ; Hirata, Koichi ; Furuhata, Tomohisa ; Mizuguchi, Tohru ; Osanai, Hiroyuki ; Yanai, Yoshiyuki ; Hata, Fumitake ; Kihara, Chikasi ; Sasaki, Kazuaki ; Oono, Keisuke ; Nakamura, Masashi ; Shibuya, Hitoshi ; Hasegawa, Itaru ; Kimura, Masami ; Watabe, Kosho ; Kobayashi, Yasuhito ; Yamaue, Hiroki ; Hirono, Seiko ; Takesue, Yoshio ; Fujiwara, Toshiyoshi ; Shinoura, Susumu ; Kimura, Hideyuki ; Iwagaki, Hiromi ; Tokunaga, Naoyuki ; Sueda, Taijiro ; Hiyama, Eiso ; Murakami, Yoshiaki ; Ohge, Hiroki ; Uemura, Kenichiro ; Tsumura, Hiroaki ; Kanehiro, Tetsuya ; Takeuchi, Hitoshi ; Tanakaya, Kouji ; Iwasaki, Mitsuhiro. / Bacteria isolated from surgical infections and its susceptibilities to antimicrobial agents - Special references to bacteria isolated between April 2010 and March 2011. In: Japanese Journal of Antibiotics. 2014 ; Vol. 67, No. 5. pp. 293-334.
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abstract = "Bacteria isolated from surgical infections during the period from April 2010 to March 2011 were investigated in a multicenter study in Japan, and the following results were obtained. In this series, 631 strains including 25 strains of Candida spp. were isolated from 170 (81.7{\%}) of 208 patients with surgical infections. Four hundred and twenty two strains were isolated from primary infections, and 184 strains were isolated from surgical site infection. From primary infections, anaerobic Gram-negative bacteria were predominant, followed by aerobic Gram-negative bacteria, while from surgical site infection aerobic Gram-positive bacteria were predominant, followed by anaerobic Gram-negative bacteria. Among aerobic Gram-positive bacteria, the isolation rate of Enterococcus spp. such as Enterococcus faecalis, Enterococcus faecium, and Enterococcus avium was highest, followed by Streptococcus spp. such as Streptococcus anginosus and Staphylococcus spp. such as Staphylococcus aureus, in this order, from primary infections, while Enterococcus spp. such as E. faecalis and E. faecium was highest, followed by Staphylococcus spp. such as S. aureus from surgical site infection. Among aerobic Gram-negative bacteria, Escherichia coli was the most predominantly isolated from primary infections, followed by Klebsiella pneumoniae, Klebsiella oxytoca, Enterobacter cloacae, and Pseudomonas aeruginosa in this order, and from surgical site infection, E. coli and P. aeruginosa were most predominantly isolated, followed by E. cloacae and K. pneumoniae. Among anaerobic Gram-positive bacteria, the isolation rates of Parvimonas micro, Eggerthella lenta, Streptococcus constellatus, Gemella morbillorum, and Collinsella aerofaciens were the highest from primary infections, and the isolation rate from surgical site infection was generally low. Among anaerobic Gram-negative bacteria, the isolation rate of Bilophila wadsworthia was the highest from primary infections, followed by, Bacteroides fragilis and Bacteroides ovatus, and from surgical site infection, B.fragilis was most predominantly isolated, followed by Bacteroides thetaiotaomicron, in this order. In this series, vancomycin-resistant MRSA (methicillin-resistant S. aureus), vancomycin-resistant Enterococcus spp. and multidrug-resistant P. aeruginosa were not observed.",
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AU - Shinagawa, Nagao

AU - Hoshikawa, Tsuyoshi

AU - Oshima, Hideki

AU - Aikawa, Naoki

AU - Sasaki, Junichi

AU - Suzuki, Masaru

AU - Serine, Kazuhiko

AU - Abe, Shinya

AU - Takeyama, Hiromitsu

AU - Wakasugi, Takehiro

AU - Mashita, Keiji

AU - Tanaka, Moritsugu

AU - Mizuno, Akira

AU - Ishikawa, Masakazu

AU - Iwai, Akihiko

AU - Saito, Takaaki

AU - Muramoto, Masayuki

AU - Kubo, Shoji

AU - Lee, Shigeru

AU - Fukuhara, Kenichiro

AU - Taniguchi, Masaaki

AU - Hirata, Koichi

AU - Furuhata, Tomohisa

AU - Mizuguchi, Tohru

AU - Osanai, Hiroyuki

AU - Yanai, Yoshiyuki

AU - Hata, Fumitake

AU - Kihara, Chikasi

AU - Sasaki, Kazuaki

AU - Oono, Keisuke

AU - Nakamura, Masashi

AU - Shibuya, Hitoshi

AU - Hasegawa, Itaru

AU - Kimura, Masami

AU - Watabe, Kosho

AU - Kobayashi, Yasuhito

AU - Yamaue, Hiroki

AU - Hirono, Seiko

AU - Takesue, Yoshio

AU - Fujiwara, Toshiyoshi

AU - Shinoura, Susumu

AU - Kimura, Hideyuki

AU - Iwagaki, Hiromi

AU - Tokunaga, Naoyuki

AU - Sueda, Taijiro

AU - Hiyama, Eiso

AU - Murakami, Yoshiaki

AU - Ohge, Hiroki

AU - Uemura, Kenichiro

AU - Tsumura, Hiroaki

AU - Kanehiro, Tetsuya

AU - Takeuchi, Hitoshi

AU - Tanakaya, Kouji

AU - Iwasaki, Mitsuhiro

PY - 2014/10/1

Y1 - 2014/10/1

N2 - Bacteria isolated from surgical infections during the period from April 2010 to March 2011 were investigated in a multicenter study in Japan, and the following results were obtained. In this series, 631 strains including 25 strains of Candida spp. were isolated from 170 (81.7%) of 208 patients with surgical infections. Four hundred and twenty two strains were isolated from primary infections, and 184 strains were isolated from surgical site infection. From primary infections, anaerobic Gram-negative bacteria were predominant, followed by aerobic Gram-negative bacteria, while from surgical site infection aerobic Gram-positive bacteria were predominant, followed by anaerobic Gram-negative bacteria. Among aerobic Gram-positive bacteria, the isolation rate of Enterococcus spp. such as Enterococcus faecalis, Enterococcus faecium, and Enterococcus avium was highest, followed by Streptococcus spp. such as Streptococcus anginosus and Staphylococcus spp. such as Staphylococcus aureus, in this order, from primary infections, while Enterococcus spp. such as E. faecalis and E. faecium was highest, followed by Staphylococcus spp. such as S. aureus from surgical site infection. Among aerobic Gram-negative bacteria, Escherichia coli was the most predominantly isolated from primary infections, followed by Klebsiella pneumoniae, Klebsiella oxytoca, Enterobacter cloacae, and Pseudomonas aeruginosa in this order, and from surgical site infection, E. coli and P. aeruginosa were most predominantly isolated, followed by E. cloacae and K. pneumoniae. Among anaerobic Gram-positive bacteria, the isolation rates of Parvimonas micro, Eggerthella lenta, Streptococcus constellatus, Gemella morbillorum, and Collinsella aerofaciens were the highest from primary infections, and the isolation rate from surgical site infection was generally low. Among anaerobic Gram-negative bacteria, the isolation rate of Bilophila wadsworthia was the highest from primary infections, followed by, Bacteroides fragilis and Bacteroides ovatus, and from surgical site infection, B.fragilis was most predominantly isolated, followed by Bacteroides thetaiotaomicron, in this order. In this series, vancomycin-resistant MRSA (methicillin-resistant S. aureus), vancomycin-resistant Enterococcus spp. and multidrug-resistant P. aeruginosa were not observed.

AB - Bacteria isolated from surgical infections during the period from April 2010 to March 2011 were investigated in a multicenter study in Japan, and the following results were obtained. In this series, 631 strains including 25 strains of Candida spp. were isolated from 170 (81.7%) of 208 patients with surgical infections. Four hundred and twenty two strains were isolated from primary infections, and 184 strains were isolated from surgical site infection. From primary infections, anaerobic Gram-negative bacteria were predominant, followed by aerobic Gram-negative bacteria, while from surgical site infection aerobic Gram-positive bacteria were predominant, followed by anaerobic Gram-negative bacteria. Among aerobic Gram-positive bacteria, the isolation rate of Enterococcus spp. such as Enterococcus faecalis, Enterococcus faecium, and Enterococcus avium was highest, followed by Streptococcus spp. such as Streptococcus anginosus and Staphylococcus spp. such as Staphylococcus aureus, in this order, from primary infections, while Enterococcus spp. such as E. faecalis and E. faecium was highest, followed by Staphylococcus spp. such as S. aureus from surgical site infection. Among aerobic Gram-negative bacteria, Escherichia coli was the most predominantly isolated from primary infections, followed by Klebsiella pneumoniae, Klebsiella oxytoca, Enterobacter cloacae, and Pseudomonas aeruginosa in this order, and from surgical site infection, E. coli and P. aeruginosa were most predominantly isolated, followed by E. cloacae and K. pneumoniae. Among anaerobic Gram-positive bacteria, the isolation rates of Parvimonas micro, Eggerthella lenta, Streptococcus constellatus, Gemella morbillorum, and Collinsella aerofaciens were the highest from primary infections, and the isolation rate from surgical site infection was generally low. Among anaerobic Gram-negative bacteria, the isolation rate of Bilophila wadsworthia was the highest from primary infections, followed by, Bacteroides fragilis and Bacteroides ovatus, and from surgical site infection, B.fragilis was most predominantly isolated, followed by Bacteroides thetaiotaomicron, in this order. In this series, vancomycin-resistant MRSA (methicillin-resistant S. aureus), vancomycin-resistant Enterococcus spp. and multidrug-resistant P. aeruginosa were not observed.

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