Autonomic cardiovascular changes during and after 14 days of head-down bed rest

Kaname Hirayanagi, Atsunori Kamiya, Satoshi Iwase, Tadaaki Mano, Tsuyoshi Sasaki, Miyuki Oinuma, Kazuyoshi Yajima

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

A 14-day, 6° head-down bed rest (HDBR) study was conducted with 12 healthy young men to determine whether there are transient responses of the cardiovascular autonomic regulatory system including cardiovascular, autonomic nervous, and cardiac baroreceptor reflex functions in the acute phases of HDBR and post-HDBR. Compared with the supine position before bed rest, the high-frequency band power (HFRRI) of RR intervals (RRIs) decreased significantly at 3, 6, and 24 h of HDBR. This tendency went on until 24 h post-HDBR. Three kinds of cardiac baroreceptor reflex sensitivity (BRS) were estimated from closed-loop approaches to simultaneously recorded spontaneous RRI and systolic arterial pressure (SAP) fluctuations. BRSsequence is based on the simultaneous changes between RRI and SAP. αLF and αHF are based on a cross-spectrum analysis for low- and high-frequency bands of RRI and SAP. Although BRSsequence decreased significantly at acute phases of both HDBR and post-HDBR, neither αLF nor αHF decreased significantly at any of the acute phases of HDBR and post-HDBR. Our results suggest that HF RRI and BRSsequence can be used effectively to reveal reductions in cardiac vagal nervous modulation on the sinus node and cardiac BRS within 24 h of both HDBR and post-HDBR.

Original languageEnglish
Pages (from-to)121-128
Number of pages8
JournalAutonomic Neuroscience: Basic and Clinical
Volume110
Issue number2
DOIs
Publication statusPublished - Feb 27 2004
Externally publishedYes

Fingerprint

Bed Rest
Head
Baroreflex
Arterial Pressure
Blood Pressure
Sinoatrial Node
Supine Position
Cardiovascular System
Spectrum Analysis

Keywords

  • Arterial pressure variability
  • Autonomic nervous system
  • Baroreceptor reflex sensitivity
  • Head-down bed rest
  • Heart rate variability

ASJC Scopus subject areas

  • Endocrine and Autonomic Systems
  • Clinical Neurology
  • Cellular and Molecular Neuroscience

Cite this

Autonomic cardiovascular changes during and after 14 days of head-down bed rest. / Hirayanagi, Kaname; Kamiya, Atsunori; Iwase, Satoshi; Mano, Tadaaki; Sasaki, Tsuyoshi; Oinuma, Miyuki; Yajima, Kazuyoshi.

In: Autonomic Neuroscience: Basic and Clinical, Vol. 110, No. 2, 27.02.2004, p. 121-128.

Research output: Contribution to journalArticle

Hirayanagi, Kaname ; Kamiya, Atsunori ; Iwase, Satoshi ; Mano, Tadaaki ; Sasaki, Tsuyoshi ; Oinuma, Miyuki ; Yajima, Kazuyoshi. / Autonomic cardiovascular changes during and after 14 days of head-down bed rest. In: Autonomic Neuroscience: Basic and Clinical. 2004 ; Vol. 110, No. 2. pp. 121-128.
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