Autologous Bone Marrow Transplantation for Polymyositis Combined with Myasthenia Gravis and Aplastic Anemia: A Case Report

Sho Mitsumune, Yasuhiro Manabe, Taijun Yunoki, Shyoichiro Kono, Kazutoshi Aoyama, Yoko Shinno, Hisashi Narai, Koji Abe

Research output: Contribution to journalArticle

Abstract

This is the first report about a patient with concomitant polymyositis (PM), myasthenia gravis (MG), and aplastic anemia (AA). A 54-year-old male developed myalgia and muscle weakness, which gradually progressed over 2 months. He was persistently affected by MG and AA. Brachium magnetic resonance imaging showed increased signal intensity in the left triceps and deltoid muscles on short tau inversion recovery images. A muscle biopsy examination revealed perifascicular atrophication and inflammatory myopathy. We diagnosed the patient with PM combined with MG and AA. He was successfully treated with an autologous bone marrow transplantation (BMT). The present case suggests that BMT is a therapeutic option for PM, MG, and AA.

Original languageEnglish
Pages (from-to)108-111
Number of pages4
JournalCase Reports in Neurology
Volume10
Issue number1
DOIs
Publication statusPublished - Feb 14 2018

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Polymyositis
Aplastic Anemia
Autologous Transplantation
Myasthenia Gravis
Bone Marrow Transplantation
Deltoid Muscle
Myositis
Myalgia
Muscle Weakness
Arm
Magnetic Resonance Imaging
Biopsy
Muscles
Therapeutics

Keywords

  • Aplastic anemia
  • Bone marrow transplantation
  • Myasthenia gravis
  • Polymyositis

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Autologous Bone Marrow Transplantation for Polymyositis Combined with Myasthenia Gravis and Aplastic Anemia : A Case Report. / Mitsumune, Sho; Manabe, Yasuhiro; Yunoki, Taijun; Kono, Shyoichiro; Aoyama, Kazutoshi; Shinno, Yoko; Narai, Hisashi; Abe, Koji.

In: Case Reports in Neurology, Vol. 10, No. 1, 14.02.2018, p. 108-111.

Research output: Contribution to journalArticle

Mitsumune, Sho ; Manabe, Yasuhiro ; Yunoki, Taijun ; Kono, Shyoichiro ; Aoyama, Kazutoshi ; Shinno, Yoko ; Narai, Hisashi ; Abe, Koji. / Autologous Bone Marrow Transplantation for Polymyositis Combined with Myasthenia Gravis and Aplastic Anemia : A Case Report. In: Case Reports in Neurology. 2018 ; Vol. 10, No. 1. pp. 108-111.
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