Autoimmune neutropenia associated with multiple sclerosis

Teruhiko Kozuka, Kensuke Kojima, Kinuyo Kaneda, Katsuto Takenaka, Yasuhiro Manabe, Yasushi Hirata, Shigenori Okuma, Hironobu Toki, Mitsune Tanimoto

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

A 53-year-old Japanese man with multiple sclerosis developed autoimmune neutropenia. The neutrophil count was consistently less than 0.2×109/l, irrespective of the disease activity of multiple sclerosis or the administration of immunosuppressive agents or granulocyte colony-stimulating factor. After high-dose γ-globulin therapy was started, temporary increases in the neutrophil count were observed. Despite a wide spectrum of clinical manifestations in multiple sclerosis, autoimmune neutropenia has never been reported previously.

Original languageEnglish
Pages (from-to)102-104
Number of pages3
JournalInternal Medicine
Volume42
Issue number1
Publication statusPublished - Jan 1 2003

Fingerprint

Neutropenia
Multiple Sclerosis
Neutrophils
Globulins
Granulocyte Colony-Stimulating Factor
Immunosuppressive Agents
Therapeutics

Keywords

  • Autoimmune neutropenia
  • Cyclosporine
  • Multiple sclerosis
  • Neutrophil antibody

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Kozuka, T., Kojima, K., Kaneda, K., Takenaka, K., Manabe, Y., Hirata, Y., ... Tanimoto, M. (2003). Autoimmune neutropenia associated with multiple sclerosis. Internal Medicine, 42(1), 102-104.

Autoimmune neutropenia associated with multiple sclerosis. / Kozuka, Teruhiko; Kojima, Kensuke; Kaneda, Kinuyo; Takenaka, Katsuto; Manabe, Yasuhiro; Hirata, Yasushi; Okuma, Shigenori; Toki, Hironobu; Tanimoto, Mitsune.

In: Internal Medicine, Vol. 42, No. 1, 01.01.2003, p. 102-104.

Research output: Contribution to journalArticle

Kozuka, T, Kojima, K, Kaneda, K, Takenaka, K, Manabe, Y, Hirata, Y, Okuma, S, Toki, H & Tanimoto, M 2003, 'Autoimmune neutropenia associated with multiple sclerosis', Internal Medicine, vol. 42, no. 1, pp. 102-104.
Kozuka T, Kojima K, Kaneda K, Takenaka K, Manabe Y, Hirata Y et al. Autoimmune neutropenia associated with multiple sclerosis. Internal Medicine. 2003 Jan 1;42(1):102-104.
Kozuka, Teruhiko ; Kojima, Kensuke ; Kaneda, Kinuyo ; Takenaka, Katsuto ; Manabe, Yasuhiro ; Hirata, Yasushi ; Okuma, Shigenori ; Toki, Hironobu ; Tanimoto, Mitsune. / Autoimmune neutropenia associated with multiple sclerosis. In: Internal Medicine. 2003 ; Vol. 42, No. 1. pp. 102-104.
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