TY - JOUR
T1 - Augmentation in cytotoxicity of lymphnode lymphocytes by OK-432
AU - Tanaka, Noriaki
AU - Gotoh, Kiyotoshi
AU - Kobayashi, Genso
AU - Gouchi, Akira
AU - Orita, Kunzo
PY - 1994/2
Y1 - 1994/2
N2 - It has been demonstrated that natural killer (NK) cell activity of lymphnode lymphocytes (LNL) is very low and hardly augmented by interferon. In this study, OK-432 was injected into the gastric cancer mass through endoscopy one week before the operation, through which NK activity of LNL was significantly increased. A single cell assay could divide the OK-432-injected patients into two groups; responder and non-responder. In responders, the increased activity induced by OK-432 was found also in the distal lymphnodes.
AB - It has been demonstrated that natural killer (NK) cell activity of lymphnode lymphocytes (LNL) is very low and hardly augmented by interferon. In this study, OK-432 was injected into the gastric cancer mass through endoscopy one week before the operation, through which NK activity of LNL was significantly increased. A single cell assay could divide the OK-432-injected patients into two groups; responder and non-responder. In responders, the increased activity induced by OK-432 was found also in the distal lymphnodes.
UR - http://www.scopus.com/inward/record.url?scp=0027953608&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0027953608&partnerID=8YFLogxK
U2 - 10.1016/0192-0561(94)90069-8
DO - 10.1016/0192-0561(94)90069-8
M3 - Article
C2 - 8181902
AN - SCOPUS:0027953608
SN - 1567-5769
VL - 16
SP - 131
EP - 135
JO - International Immunopharmacology
JF - International Immunopharmacology
IS - 2
ER -
