Treatment of an allylic tin-bearing chiral acetal 1a with TiCl 4-PPh3 gives the (2S, 3R) isomer 2 with high diastereoselectivity (2 : 3 = 93 : 7), whereas the reaction of an allylic silane derivative 1f affords predominantly the (2R, 3S) isomer 3 (2 : 3 = 37 : 63).
|Number of pages||2|
|Journal||Journal of the Chemical Society, Chemical Communications|
|Publication status||Published - Dec 1 1994|
ASJC Scopus subject areas
- Molecular Medicine