Abstract
Tetrahydro-β-carbolines, (S)-tetrahydroharman (8a) and (S)-1-phenyltetrahydro-β-carboline (8b), were asymmetrically synthesized starting from (R)-phenylglycinol and 1-benzyl-3-(2-bromoethyl)indole (1). Asymmetric synthesis of the 9-thio analogue (15) of 8a was also achieved.
| Original language | English |
|---|---|
| Pages (from-to) | 3338-3340 |
| Number of pages | 3 |
| Journal | Chemical and Pharmaceutical Bulletin |
| Volume | 39 |
| Issue number | 12 |
| Publication status | Published - 1991 |
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ASJC Scopus subject areas
- Chemistry(all)
- Organic Chemistry
- Drug Discovery
- Pharmacology
Cite this
Asymmetric syntheses of 1-alkyltetrahydro-β-carbolines and a 9-thio analogue. / Qais, N.; Nakao, N.; Hashigaki, K.; Takeuchi, Yasuo; Yamato, M.
In: Chemical and Pharmaceutical Bulletin, Vol. 39, No. 12, 1991, p. 3338-3340.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Asymmetric syntheses of 1-alkyltetrahydro-β-carbolines and a 9-thio analogue
AU - Qais, N.
AU - Nakao, N.
AU - Hashigaki, K.
AU - Takeuchi, Yasuo
AU - Yamato, M.
PY - 1991
Y1 - 1991
N2 - Tetrahydro-β-carbolines, (S)-tetrahydroharman (8a) and (S)-1-phenyltetrahydro-β-carboline (8b), were asymmetrically synthesized starting from (R)-phenylglycinol and 1-benzyl-3-(2-bromoethyl)indole (1). Asymmetric synthesis of the 9-thio analogue (15) of 8a was also achieved.
AB - Tetrahydro-β-carbolines, (S)-tetrahydroharman (8a) and (S)-1-phenyltetrahydro-β-carboline (8b), were asymmetrically synthesized starting from (R)-phenylglycinol and 1-benzyl-3-(2-bromoethyl)indole (1). Asymmetric synthesis of the 9-thio analogue (15) of 8a was also achieved.
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UR - http://www.scopus.com/inward/citedby.url?scp=0026344213&partnerID=8YFLogxK
M3 - Article
VL - 39
SP - 3338
EP - 3340
JO - Chemical and Pharmaceutical Bulletin
JF - Chemical and Pharmaceutical Bulletin
SN - 0009-2363
IS - 12
ER -