Abstract
Tetrahydro-β-carbolines, (S)-tetrahydroharman (8a) and (S)-1-phenyltetrahydro-β-carboline (8b), were asymmetrically synthesized starting from (R)-phenylglycinol and 1-benzy1-3-(2-bromoethy)indole (1). Asymmetric synthesis of the 9-thio analogue (15) of 8a was also achieved.
| Original language | English |
|---|---|
| Pages (from-to) | 3338-3340 |
| Number of pages | 3 |
| Journal | Chemical and Pharmaceutical Bulletin |
| Volume | 39 |
| Issue number | 12 |
| DOIs | |
| Publication status | Published - 1991 |
Keywords
- 3-c]pyridine phenylglycinol asymmetric synthesis
- 5]thieno[2
- carboline (S)-tetrahydroharman (S)-aryltetrahydro-β
- carboline tetrahydroberfzo[4
- tetrahydro-β
ASJC Scopus subject areas
- Chemistry(all)
- Drug Discovery
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Cite this
Qais, N., Nakao, N., Hashigaki, K., Takeuchl, Y., & Yamato, M. (1991). Asymmetric Syntheses of 1-alkyltetrahydro-β-carbolines And A 9-Thio Analogue. Chemical and Pharmaceutical Bulletin, 39(12), 3338-3340. https://doi.org/10.1248/cpb.39.3338