TY - JOUR
T1 - Associations of preterm births with child health and development
T2 - Japanese population-based study
AU - Kato, Tsuguhiko
AU - Yorifuji, Takashi
AU - Inoue, Sachiko
AU - Yamakawa, Michiyo
AU - Doi, Hiroyuki
AU - Kawachi, Ichiro
PY - 2013/12
Y1 - 2013/12
N2 - Objective To examine associations between the duration of gestation and health and development outcomes at 2.5 years and 5.5 years using a Japanese population-based longitudinal survey (n = 47â€̂015). Study design Hospitalization was used as an indicator of physical health, and responses to questions about age-appropriate behaviors were used as an indicator of behavioral development. We conducted logistic regression analyses controlling for a set of neonatal and family factors. We also estimated population-attributable fractions. Results We observed a steady increase toward shorter duration of gestation in the risk of hospitalizations at age 2.5 years and 5.5 years and developmental delays at 2.5 years (Plinear trend <.001 for all outcomes). We found associations only between extremely preterm birth and delayed behavioral development at age 5.5 years. Conclusion There is a linear relationship between shorter duration of gestation and increased risk of later health and developmental problems. In line with Rose's "population paradox," the population-attributable risks for these problems are greater for moderately preterm infants compared with extremely preterm infants.
AB - Objective To examine associations between the duration of gestation and health and development outcomes at 2.5 years and 5.5 years using a Japanese population-based longitudinal survey (n = 47â€̂015). Study design Hospitalization was used as an indicator of physical health, and responses to questions about age-appropriate behaviors were used as an indicator of behavioral development. We conducted logistic regression analyses controlling for a set of neonatal and family factors. We also estimated population-attributable fractions. Results We observed a steady increase toward shorter duration of gestation in the risk of hospitalizations at age 2.5 years and 5.5 years and developmental delays at 2.5 years (Plinear trend <.001 for all outcomes). We found associations only between extremely preterm birth and delayed behavioral development at age 5.5 years. Conclusion There is a linear relationship between shorter duration of gestation and increased risk of later health and developmental problems. In line with Rose's "population paradox," the population-attributable risks for these problems are greater for moderately preterm infants compared with extremely preterm infants.
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U2 - 10.1016/j.jpeds.2013.07.004
DO - 10.1016/j.jpeds.2013.07.004
M3 - Article
C2 - 23968745
AN - SCOPUS:84888339388
VL - 163
SP - 1578-1584.e4
JO - Journal of Pediatrics
JF - Journal of Pediatrics
SN - 0022-3476
IS - 6
ER -