TY - JOUR
T1 - Associations of preterm births with child health and development
T2 - Japanese population-based study
AU - Kato, Tsuguhiko
AU - Yorifuji, Takashi
AU - Inoue, Sachiko
AU - Yamakawa, Michiyo
AU - Doi, Hiroyuki
AU - Kawachi, Ichiro
N1 - Funding Information:
Supported in part by Health and Labour Sciences Research and the Sumitomo Foundation . The sponsors have no involvement in deciding the study design, the collection, analysis, and interpretation of data, the writing of the report, and the decision to submit the paper for publication. The authors declare no conflicts of interest.
PY - 2013/12
Y1 - 2013/12
N2 - Objective To examine associations between the duration of gestation and health and development outcomes at 2.5 years and 5.5 years using a Japanese population-based longitudinal survey (n = 47â€̂015). Study design Hospitalization was used as an indicator of physical health, and responses to questions about age-appropriate behaviors were used as an indicator of behavioral development. We conducted logistic regression analyses controlling for a set of neonatal and family factors. We also estimated population-attributable fractions. Results We observed a steady increase toward shorter duration of gestation in the risk of hospitalizations at age 2.5 years and 5.5 years and developmental delays at 2.5 years (Plinear trend <.001 for all outcomes). We found associations only between extremely preterm birth and delayed behavioral development at age 5.5 years. Conclusion There is a linear relationship between shorter duration of gestation and increased risk of later health and developmental problems. In line with Rose's "population paradox," the population-attributable risks for these problems are greater for moderately preterm infants compared with extremely preterm infants.
AB - Objective To examine associations between the duration of gestation and health and development outcomes at 2.5 years and 5.5 years using a Japanese population-based longitudinal survey (n = 47â€̂015). Study design Hospitalization was used as an indicator of physical health, and responses to questions about age-appropriate behaviors were used as an indicator of behavioral development. We conducted logistic regression analyses controlling for a set of neonatal and family factors. We also estimated population-attributable fractions. Results We observed a steady increase toward shorter duration of gestation in the risk of hospitalizations at age 2.5 years and 5.5 years and developmental delays at 2.5 years (Plinear trend <.001 for all outcomes). We found associations only between extremely preterm birth and delayed behavioral development at age 5.5 years. Conclusion There is a linear relationship between shorter duration of gestation and increased risk of later health and developmental problems. In line with Rose's "population paradox," the population-attributable risks for these problems are greater for moderately preterm infants compared with extremely preterm infants.
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U2 - 10.1016/j.jpeds.2013.07.004
DO - 10.1016/j.jpeds.2013.07.004
M3 - Article
C2 - 23968745
AN - SCOPUS:84888339388
VL - 163
SP - 1578-1584.e4
JO - Journal of Pediatrics
JF - Journal of Pediatrics
SN - 0022-3476
IS - 6
ER -