Association study of CAG repeats in the KCNN3 gene in Japanese patients with schizophrenia, schizoaffective disorder and bipolar disorder

Hiroshi Ujike; Ayako Yamamoto; Yuji Tanaka; Yasushi Takehisa; Manabu Takaki; Toshihiko Taked; Masafumi Kodama; Shigetoshi Kuroda

doi:10.1016/S0165-1781(01)00229-3

Association study of CAG repeats in the KCNN3 gene in Japanese patients with schizophrenia, schizoaffective disorder and bipolar disorder

Hiroshi Ujike, Ayako Yamamoto, Yuji Tanaka, Yasushi Takehisa, Manabu Takaki, Toshihiko Taked, Masafumi Kodama, Shigetoshi Kuroda

University Hospital

Research output: Contribution to journal › Article › peer-review

20 Citations (Scopus)

Abstract

To investigate a possible involvement of expanded triplet repeats of genome in the genomes of patients with endogenous psychoses, we examined a CAG repeat polymorphism in the coding region of the KCNN3 gene in schizophrenia, schizoaffective disorder, bipolar disorder and controls of the Japanese population. There were no significant differences in the CAG repeat number of longer or shorter alleles among the four diagnostic groups or among the schizophreniahebephrenic and paranoid subtypes.

Original language	English
Pages (from-to)	203-207
Number of pages	5
Journal	Psychiatry research
Volume	101
Issue number	3
DOIs	https://doi.org/10.1016/S0165-1781(01)00229-3
Publication status	Published - 2001

Keywords

Anticipation
Potassium channel
Trinucleotide repeat
hSKCA3

ASJC Scopus subject areas

Psychiatry and Mental health
Biological Psychiatry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/S0165-1781(01)00229-3

Cite this

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title = "Association study of CAG repeats in the KCNN3 gene in Japanese patients with schizophrenia, schizoaffective disorder and bipolar disorder",

abstract = "To investigate a possible involvement of expanded triplet repeats of genome in the genomes of patients with endogenous psychoses, we examined a CAG repeat polymorphism in the coding region of the KCNN3 gene in schizophrenia, schizoaffective disorder, bipolar disorder and controls of the Japanese population. There were no significant differences in the CAG repeat number of longer or shorter alleles among the four diagnostic groups or among the schizophreniahebephrenic and paranoid subtypes.",

keywords = "Anticipation, Potassium channel, Trinucleotide repeat, hSKCA3",

author = "Hiroshi Ujike and Ayako Yamamoto and Yuji Tanaka and Yasushi Takehisa and Manabu Takaki and Toshihiko Taked and Masafumi Kodama and Shigetoshi Kuroda",

note = "Funding Information: The present study was supported in part by a grant from Zikei Psychiatric Hospital (Okayama, Japan).",

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doi = "10.1016/S0165-1781(01)00229-3",

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T1 - Association study of CAG repeats in the KCNN3 gene in Japanese patients with schizophrenia, schizoaffective disorder and bipolar disorder

AU - Ujike, Hiroshi

AU - Yamamoto, Ayako

AU - Tanaka, Yuji

AU - Takehisa, Yasushi

AU - Takaki, Manabu

AU - Taked, Toshihiko

AU - Kodama, Masafumi

AU - Kuroda, Shigetoshi

N1 - Funding Information: The present study was supported in part by a grant from Zikei Psychiatric Hospital (Okayama, Japan).

PY - 2001

Y1 - 2001

N2 - To investigate a possible involvement of expanded triplet repeats of genome in the genomes of patients with endogenous psychoses, we examined a CAG repeat polymorphism in the coding region of the KCNN3 gene in schizophrenia, schizoaffective disorder, bipolar disorder and controls of the Japanese population. There were no significant differences in the CAG repeat number of longer or shorter alleles among the four diagnostic groups or among the schizophreniahebephrenic and paranoid subtypes.

AB - To investigate a possible involvement of expanded triplet repeats of genome in the genomes of patients with endogenous psychoses, we examined a CAG repeat polymorphism in the coding region of the KCNN3 gene in schizophrenia, schizoaffective disorder, bipolar disorder and controls of the Japanese population. There were no significant differences in the CAG repeat number of longer or shorter alleles among the four diagnostic groups or among the schizophreniahebephrenic and paranoid subtypes.

KW - Anticipation

KW - Potassium channel

KW - Trinucleotide repeat

KW - hSKCA3

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JO - Psychiatry Research

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Association study of CAG repeats in the KCNN3 gene in Japanese patients with schizophrenia, schizoaffective disorder and bipolar disorder

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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