Association study of CAG repeats in the KCNN3 gene in Japanese patients with schizophrenia, schizoaffective disorder and bipolar disorder

Hiroshi Ujike, Ayako Yamamoto, Yuji Tanaka, Yasushi Takehisa, Manabu Takaki, Toshihiko Taked, Masafumi Kodama, Shigetoshi Kuroda

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

To investigate a possible involvement of expanded triplet repeats of genome in the genomes of patients with endogenous psychoses, we examined a CAG repeat polymorphism in the coding region of the KCNN3 gene in schizophrenia, schizoaffective disorder, bipolar disorder and controls of the Japanese population. There were no significant differences in the CAG repeat number of longer or shorter alleles among the four diagnostic groups or among the schizophreniahebephrenic and paranoid subtypes.

Original languageEnglish
Pages (from-to)203-207
Number of pages5
JournalPsychiatry research
Volume101
Issue number3
DOIs
Publication statusPublished - Jan 1 2001

Keywords

  • Anticipation
  • Potassium channel
  • Trinucleotide repeat
  • hSKCA3

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

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