Association of dietary fat and carbohydrate consumption and predicted ten-year risk for developing coronary heart disease in a general Japanese population

Akira Minoura, Da Hong Wang, Yoshie Sato, Yu Zou, Noriko Sakano, Masayuki Kubo, Kei Takemoto, Chie Masatomr, Keiki Ogino

Research output: Contribution to journalArticle

Abstract

We examined the relationships between dietary carbohydrate, protein, fat, and the ratio of n6/n3 fatty acid intakes with the predicted 10-year coronary heart disease (CHD) risk in a general Japanese population. We used the Framingham risk score to determine the 10-year CHD risk of the subjects, who were employees of 6 companies in a single prefecture in Japan. After excluding the subjects who reported any history of angina pectoris, myocardial infarction, diabetes, or cancer, and those with missing data resulting in the inability of estimation of 10-year CHD risk and food intakes, the final data analysis was carried out for 809 subjects. The logistic regression models revealed a significantly increased odds ratio of 10-year CHD risk in the subjects with the highest tertile of carbohydrate intake (% energy) (odds ratio 3.64, 95% CI, 2.07-6.40); after adjustment for other variables, the odds ratio for the 10-year CHD risk was also higher in the subjects with the highest tertile of carbohydrate intake (odds ratio 1.72, 95% CI, 0.704.25). We also found that fat intake and the ratio of n6/n3 fatty acids were inversely associated with the predicted 10-year CHD risk (p for trend <0.01). The present findings added evidence of a positive association of dietary carbohydrate and inverse associations of total fat and n6/n3 fatty acid ratio with the predicted 10-year CHD risk in a general Japanese population.

Original languageEnglish
Pages (from-to)129-135
Number of pages7
JournalActa Medica Okayama
Volume68
Issue number3
Publication statusPublished - 2014

Fingerprint

Dietary Carbohydrates
Dietary Fats
Coronary Disease
Population
Omega-3 Fatty Acids
Odds Ratio
Fats
Logistic Models
Carbohydrates
Dietary Proteins
Angina Pectoris
Medical problems
Energy Intake
Logistics
Japan
Eating
Myocardial Infarction
Personnel

Keywords

  • 10-year coronary heart disease risk
  • Carbohydrate intake
  • Fat intake
  • Japanese
  • Ratio of n6/n3 fatty acids

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Association of dietary fat and carbohydrate consumption and predicted ten-year risk for developing coronary heart disease in a general Japanese population. / Minoura, Akira; Wang, Da Hong; Sato, Yoshie; Zou, Yu; Sakano, Noriko; Kubo, Masayuki; Takemoto, Kei; Masatomr, Chie; Ogino, Keiki.

In: Acta Medica Okayama, Vol. 68, No. 3, 2014, p. 129-135.

Research output: Contribution to journalArticle

Minoura, A, Wang, DH, Sato, Y, Zou, Y, Sakano, N, Kubo, M, Takemoto, K, Masatomr, C & Ogino, K 2014, 'Association of dietary fat and carbohydrate consumption and predicted ten-year risk for developing coronary heart disease in a general Japanese population', Acta Medica Okayama, vol. 68, no. 3, pp. 129-135.
Minoura, Akira ; Wang, Da Hong ; Sato, Yoshie ; Zou, Yu ; Sakano, Noriko ; Kubo, Masayuki ; Takemoto, Kei ; Masatomr, Chie ; Ogino, Keiki. / Association of dietary fat and carbohydrate consumption and predicted ten-year risk for developing coronary heart disease in a general Japanese population. In: Acta Medica Okayama. 2014 ; Vol. 68, No. 3. pp. 129-135.
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