Association of arginase I or nitric oxide-related factors with job strain in healthy workers

Keiki Ogino, Tatsuo Ito, Eri Eguchi, Kenjiro Nagaoka

Research output: Contribution to journalArticle

Abstract

This study evaluated the associations between job strain and arginase I in 378 healthy Japanese factory workers by a cross-sectional study measuring nitric oxide (NO)-related parameters (arginase I, L-arginine, exhaled nitric oxide (FeNO), and NOx), clinical parameters, and job strain using a Japanese version of the Job Content Questionnaire by Karasek. Arginase I and FEV1% were negatively correlated with job strain and positively correlated with job control and social support. FeNO and hs-CRP were negatively correlated with job strain. Multiple regression analysis showed negative association of arginase I with job strain and positive association with job control and social support in females. It is concluded that serum levels of arginase I may be useful biomarkers for the diagnosis of job stress in healthy female workers, although many factors can be influencing the data.

Original languageEnglish
Article numbere0175696
JournalPLoS One
Volume12
Issue number4
DOIs
Publication statusPublished - Apr 1 2017

Fingerprint

Arginase
arginase
nitric oxide
Nitric Oxide
Social Support
Association reactions
Biomarkers
Regression analysis
Arginine
Industrial plants
Cross-Sectional Studies
Regression Analysis
factories
cross-sectional studies
Serum
arginine
biomarkers
regression analysis
questionnaires

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

Cite this

Association of arginase I or nitric oxide-related factors with job strain in healthy workers. / Ogino, Keiki; Ito, Tatsuo; Eguchi, Eri; Nagaoka, Kenjiro.

In: PLoS One, Vol. 12, No. 4, e0175696, 01.04.2017.

Research output: Contribution to journalArticle

@article{717f53f68dac44faa1da1541831aa2ba,
title = "Association of arginase I or nitric oxide-related factors with job strain in healthy workers",
abstract = "This study evaluated the associations between job strain and arginase I in 378 healthy Japanese factory workers by a cross-sectional study measuring nitric oxide (NO)-related parameters (arginase I, L-arginine, exhaled nitric oxide (FeNO), and NOx), clinical parameters, and job strain using a Japanese version of the Job Content Questionnaire by Karasek. Arginase I and FEV1{\%} were negatively correlated with job strain and positively correlated with job control and social support. FeNO and hs-CRP were negatively correlated with job strain. Multiple regression analysis showed negative association of arginase I with job strain and positive association with job control and social support in females. It is concluded that serum levels of arginase I may be useful biomarkers for the diagnosis of job stress in healthy female workers, although many factors can be influencing the data.",
author = "Keiki Ogino and Tatsuo Ito and Eri Eguchi and Kenjiro Nagaoka",
year = "2017",
month = "4",
day = "1",
doi = "10.1371/journal.pone.0175696",
language = "English",
volume = "12",
journal = "PLoS One",
issn = "1932-6203",
publisher = "Public Library of Science",
number = "4",

}

TY - JOUR

T1 - Association of arginase I or nitric oxide-related factors with job strain in healthy workers

AU - Ogino, Keiki

AU - Ito, Tatsuo

AU - Eguchi, Eri

AU - Nagaoka, Kenjiro

PY - 2017/4/1

Y1 - 2017/4/1

N2 - This study evaluated the associations between job strain and arginase I in 378 healthy Japanese factory workers by a cross-sectional study measuring nitric oxide (NO)-related parameters (arginase I, L-arginine, exhaled nitric oxide (FeNO), and NOx), clinical parameters, and job strain using a Japanese version of the Job Content Questionnaire by Karasek. Arginase I and FEV1% were negatively correlated with job strain and positively correlated with job control and social support. FeNO and hs-CRP were negatively correlated with job strain. Multiple regression analysis showed negative association of arginase I with job strain and positive association with job control and social support in females. It is concluded that serum levels of arginase I may be useful biomarkers for the diagnosis of job stress in healthy female workers, although many factors can be influencing the data.

AB - This study evaluated the associations between job strain and arginase I in 378 healthy Japanese factory workers by a cross-sectional study measuring nitric oxide (NO)-related parameters (arginase I, L-arginine, exhaled nitric oxide (FeNO), and NOx), clinical parameters, and job strain using a Japanese version of the Job Content Questionnaire by Karasek. Arginase I and FEV1% were negatively correlated with job strain and positively correlated with job control and social support. FeNO and hs-CRP were negatively correlated with job strain. Multiple regression analysis showed negative association of arginase I with job strain and positive association with job control and social support in females. It is concluded that serum levels of arginase I may be useful biomarkers for the diagnosis of job stress in healthy female workers, although many factors can be influencing the data.

UR - http://www.scopus.com/inward/record.url?scp=85017562001&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85017562001&partnerID=8YFLogxK

U2 - 10.1371/journal.pone.0175696

DO - 10.1371/journal.pone.0175696

M3 - Article

C2 - 28403218

AN - SCOPUS:85017562001

VL - 12

JO - PLoS One

JF - PLoS One

SN - 1932-6203

IS - 4

M1 - e0175696

ER -