Associated and predictive factors of sleep disturbance in advanced cancer patients

Tatsuo Akechi, Toru Okuyama, Nobuya Akizuki, Ken Shimizu, Masatoshi Inagaki, Maiko Fujimori, Yasuo Shima, Toshiaki A. Furukawa, Yosuke Uchitomi

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

Little attention has been paid to sleep disturbance experienced by advanced cancer patients. The purpose of the present study was to investigate longitudinal change in sleep disturbance and to identify factors that associated with and predicted sleep disturbance among 209 consecutive terminally ill cancer patients. Patients were assessed twice for sleep disturbance by one item of the structured clinical interview for assessing depression, once at the time of their registration with a palliative care unit (PCU) (baseline) and again at the time of their PCU admission (follow-up), and possible associated medical and psychosocial factors were evaluated. The proportions of patients with obvious sleep disturbance at baseline and follow-up were 15.3 and 25.9%, respectively. Sixty-seven percent of the subjects showed some sleep status changes, including both aggravation and improvement, between baseline and follow-up. Being younger, having diarrhea and living alone were significantly associated with sleep disturbance at baseline, and the increase of psychological distress was the only significant predictive factor for sleep disturbance at follow-up. These findings suggest that psychological distress is a possible key cause of sleep disturbance and management of psychological distress may be one promising strategy for prevention of sleep disturbance among advanced cancer patients.

Original languageEnglish
Pages (from-to)888-894
Number of pages7
JournalPsycho-Oncology
Volume16
Issue number10
DOIs
Publication statusPublished - Oct 2007
Externally publishedYes

Fingerprint

sleep
Sleep
cancer
Neoplasms
Psychology
Palliative Care
medical factors
Terminally Ill
psychosocial factors
Diarrhea
Interviews
Depression
cause
interview

Keywords

  • Cancer
  • Oncology
  • Prevention
  • Psychological distress
  • Sleep disturbance

ASJC Scopus subject areas

  • Oncology
  • Psychology(all)
  • Social Sciences (miscellaneous)

Cite this

Akechi, T., Okuyama, T., Akizuki, N., Shimizu, K., Inagaki, M., Fujimori, M., ... Uchitomi, Y. (2007). Associated and predictive factors of sleep disturbance in advanced cancer patients. Psycho-Oncology, 16(10), 888-894. https://doi.org/10.1002/pon.1122

Associated and predictive factors of sleep disturbance in advanced cancer patients. / Akechi, Tatsuo; Okuyama, Toru; Akizuki, Nobuya; Shimizu, Ken; Inagaki, Masatoshi; Fujimori, Maiko; Shima, Yasuo; Furukawa, Toshiaki A.; Uchitomi, Yosuke.

In: Psycho-Oncology, Vol. 16, No. 10, 10.2007, p. 888-894.

Research output: Contribution to journalArticle

Akechi, T, Okuyama, T, Akizuki, N, Shimizu, K, Inagaki, M, Fujimori, M, Shima, Y, Furukawa, TA & Uchitomi, Y 2007, 'Associated and predictive factors of sleep disturbance in advanced cancer patients', Psycho-Oncology, vol. 16, no. 10, pp. 888-894. https://doi.org/10.1002/pon.1122
Akechi T, Okuyama T, Akizuki N, Shimizu K, Inagaki M, Fujimori M et al. Associated and predictive factors of sleep disturbance in advanced cancer patients. Psycho-Oncology. 2007 Oct;16(10):888-894. https://doi.org/10.1002/pon.1122
Akechi, Tatsuo ; Okuyama, Toru ; Akizuki, Nobuya ; Shimizu, Ken ; Inagaki, Masatoshi ; Fujimori, Maiko ; Shima, Yasuo ; Furukawa, Toshiaki A. ; Uchitomi, Yosuke. / Associated and predictive factors of sleep disturbance in advanced cancer patients. In: Psycho-Oncology. 2007 ; Vol. 16, No. 10. pp. 888-894.
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