Abstract
Vibrio vulnificus, a ubiquitous microorganism in aquatic environments, causes serious septicemia to the immunocompromised host. In addition to protoheme, this species can utilize FeTCPP [ferric tetrakis (4-carboxyphenyl) porphine] as an iron source. In the present study, heme c bound covalently to the protein in cytochrome c, as well as the Fe-TCPP complex formed with a nanopeptide with a high affinity, was found to be useful iron sources for V. vulnificus. This bacterium was also revealed to use Zn-TCPP as a single zinc source. However, other metalloporphyrins such as Mn-TCPP and Pt-TCPP delayed the bacterial growth in the broth containing Fe-TCPP, suggesting interference in the iron assimilation. These results indicate that V. vulnificus may acquire metal ions from both free and peptide-bound metalloporphyrins.
Original language | English |
---|---|
Pages (from-to) | 1-6 |
Number of pages | 6 |
Journal | Biocontrol science |
Volume | 15 |
Issue number | 1 |
DOIs | |
Publication status | Published - 2010 |
Keywords
- Heme
- Iron source
- Metalloporphyrin
- Vibrio vulnificus
ASJC Scopus subject areas
- Applied Microbiology and Biotechnology
- Public Health, Environmental and Occupational Health