Abstract
In patients with hypertrophic cardiomyopathy (HCM), we conducted cine magnetic resonance imaging (MRI) studies in which our objectives were to quantify the regional early diastolic function of the left ventricle and to evaluate the relationship between regional diastolic function and hypertrophy. Short-axis images of the left ventricle were recorded by cine MRI in 8 control patients and 24 patients with HCM. The images were then divided into 10 blocks to evaluate regional early diastolic function. The regional wall-thickness-time curve, the radius-time curve, and their first- derivative curves were computed for each of the 10 blocks. There was no difference between the time-to-peak-radius-increasing ratio and the time-to- peak-wall-thickness-thinning ratio in the 10 blocks in the control patients. These 2 parameters in the patients with HCM were significantly longer than those in the control patients. There was also a significant linear correlation between the time-to-peak-wall-thickness-thinning ratio and regional wall thickness. Cine MRI was useful for evaluating regional early diastolic function, which is apparently related to regional hypertrophy, in patients with HCM.
| Original language | English |
|---|---|
| Pages (from-to) | 917-924 |
| Number of pages | 8 |
| Journal | Japanese Circulation Journal |
| Volume | 60 |
| Issue number | 12 |
| DOIs | |
| Publication status | Published - Dec 1996 |
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Keywords
- Cine magnetic resonance imaging
- Hypertrophic cardiomyopathy
- Regional early diastolic function
- Regional hypertrophy
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
- Physiology
Cite this
Assessment of regional early diastolic function using cine magnetic resonance imaging in patients with hypertrophic cardiomyopathy. / Yamanari, Hiroshi; Morita, Hiroshi; Nakamura, Kazufumi; Mizuo, Kouzou; Sato, Tetsuya; Ohe, Tohru.
In: Japanese Circulation Journal, Vol. 60, No. 12, 12.1996, p. 917-924.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Assessment of regional early diastolic function using cine magnetic resonance imaging in patients with hypertrophic cardiomyopathy
AU - Yamanari, Hiroshi
AU - Morita, Hiroshi
AU - Nakamura, Kazufumi
AU - Mizuo, Kouzou
AU - Sato, Tetsuya
AU - Ohe, Tohru
PY - 1996/12
Y1 - 1996/12
N2 - In patients with hypertrophic cardiomyopathy (HCM), we conducted cine magnetic resonance imaging (MRI) studies in which our objectives were to quantify the regional early diastolic function of the left ventricle and to evaluate the relationship between regional diastolic function and hypertrophy. Short-axis images of the left ventricle were recorded by cine MRI in 8 control patients and 24 patients with HCM. The images were then divided into 10 blocks to evaluate regional early diastolic function. The regional wall-thickness-time curve, the radius-time curve, and their first- derivative curves were computed for each of the 10 blocks. There was no difference between the time-to-peak-radius-increasing ratio and the time-to- peak-wall-thickness-thinning ratio in the 10 blocks in the control patients. These 2 parameters in the patients with HCM were significantly longer than those in the control patients. There was also a significant linear correlation between the time-to-peak-wall-thickness-thinning ratio and regional wall thickness. Cine MRI was useful for evaluating regional early diastolic function, which is apparently related to regional hypertrophy, in patients with HCM.
AB - In patients with hypertrophic cardiomyopathy (HCM), we conducted cine magnetic resonance imaging (MRI) studies in which our objectives were to quantify the regional early diastolic function of the left ventricle and to evaluate the relationship between regional diastolic function and hypertrophy. Short-axis images of the left ventricle were recorded by cine MRI in 8 control patients and 24 patients with HCM. The images were then divided into 10 blocks to evaluate regional early diastolic function. The regional wall-thickness-time curve, the radius-time curve, and their first- derivative curves were computed for each of the 10 blocks. There was no difference between the time-to-peak-radius-increasing ratio and the time-to- peak-wall-thickness-thinning ratio in the 10 blocks in the control patients. These 2 parameters in the patients with HCM were significantly longer than those in the control patients. There was also a significant linear correlation between the time-to-peak-wall-thickness-thinning ratio and regional wall thickness. Cine MRI was useful for evaluating regional early diastolic function, which is apparently related to regional hypertrophy, in patients with HCM.
KW - Cine magnetic resonance imaging
KW - Hypertrophic cardiomyopathy
KW - Regional early diastolic function
KW - Regional hypertrophy
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UR - http://www.scopus.com/inward/citedby.url?scp=0030482691&partnerID=8YFLogxK
U2 - 10.1253/jcj.60.917
DO - 10.1253/jcj.60.917
M3 - Article
VL - 60
SP - 917
EP - 924
JO - Circulation Journal
JF - Circulation Journal
SN - 1346-9843
IS - 12
ER -