Abstract
Background: Due to its easy applicability, pulse wave has been proposed as a surrogate of electrocardiogram (ECG) for the analysis of heart rate variability (HRV). However, its smoother waveform precludes accurate measurement of pulse-to-pulse interval by fiducial-point algorithms. Here we report a pulse frequency demodulation (PFDM) technique as a method for extracting instantaneous pulse rate function directly from pulse wave signal and its usefulness for assessing pulse rate variability (PRV). Methods: Simulated pulse wave signals with known pulse interval functions and actual pulse wave signals obtained from 30 subjects with a trans-dermal pulse wave device were analyzed by PFDM. The results were compared with heart rate and HRV assessed from simultaneously recorded ECG. Results: Analysis of simulated data revealed that the PFDM faithfully demodulates source interval function with preserving the frequency characteristics of the function, even when the intervals fluctuate rapidly over a wide range and when the signals include fluctuations in pulse height and baseline. Analysis of actual data revealed that individual means of low and high frequency components of PRV showed good agreement with those of HRV (intraclass correlation coefficient, 0.997 and 0.981, respectively). Conclusions: The PFDM of pulse wave signal provides a reliable assessment of PRV. Given the popularity of pulse wave equipments, PFDM may open new ways to the studies of long-term assessment of cardiovascular variability and dynamics.
| Original language | English |
|---|---|
| Article number | 62 |
| Journal | BioMedical Engineering Online |
| Volume | 4 |
| DOIs | |
| Publication status | Published - Nov 1 2005 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Radiological and Ultrasound Technology
- Biomaterials
- Biomedical Engineering
- Radiology Nuclear Medicine and imaging
Cite this
Assessment of pulse rate variability by the method of pulse frequency demodulation. / Hayano, Junichiro; Barros, Allan Kardec; Kamiya, Atsunori; Ohte, Nobuyuki; Yasuma, Fumihiko.
In: BioMedical Engineering Online, Vol. 4, 62, 01.11.2005.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Assessment of pulse rate variability by the method of pulse frequency demodulation
AU - Hayano, Junichiro
AU - Barros, Allan Kardec
AU - Kamiya, Atsunori
AU - Ohte, Nobuyuki
AU - Yasuma, Fumihiko
PY - 2005/11/1
Y1 - 2005/11/1
N2 - Background: Due to its easy applicability, pulse wave has been proposed as a surrogate of electrocardiogram (ECG) for the analysis of heart rate variability (HRV). However, its smoother waveform precludes accurate measurement of pulse-to-pulse interval by fiducial-point algorithms. Here we report a pulse frequency demodulation (PFDM) technique as a method for extracting instantaneous pulse rate function directly from pulse wave signal and its usefulness for assessing pulse rate variability (PRV). Methods: Simulated pulse wave signals with known pulse interval functions and actual pulse wave signals obtained from 30 subjects with a trans-dermal pulse wave device were analyzed by PFDM. The results were compared with heart rate and HRV assessed from simultaneously recorded ECG. Results: Analysis of simulated data revealed that the PFDM faithfully demodulates source interval function with preserving the frequency characteristics of the function, even when the intervals fluctuate rapidly over a wide range and when the signals include fluctuations in pulse height and baseline. Analysis of actual data revealed that individual means of low and high frequency components of PRV showed good agreement with those of HRV (intraclass correlation coefficient, 0.997 and 0.981, respectively). Conclusions: The PFDM of pulse wave signal provides a reliable assessment of PRV. Given the popularity of pulse wave equipments, PFDM may open new ways to the studies of long-term assessment of cardiovascular variability and dynamics.
AB - Background: Due to its easy applicability, pulse wave has been proposed as a surrogate of electrocardiogram (ECG) for the analysis of heart rate variability (HRV). However, its smoother waveform precludes accurate measurement of pulse-to-pulse interval by fiducial-point algorithms. Here we report a pulse frequency demodulation (PFDM) technique as a method for extracting instantaneous pulse rate function directly from pulse wave signal and its usefulness for assessing pulse rate variability (PRV). Methods: Simulated pulse wave signals with known pulse interval functions and actual pulse wave signals obtained from 30 subjects with a trans-dermal pulse wave device were analyzed by PFDM. The results were compared with heart rate and HRV assessed from simultaneously recorded ECG. Results: Analysis of simulated data revealed that the PFDM faithfully demodulates source interval function with preserving the frequency characteristics of the function, even when the intervals fluctuate rapidly over a wide range and when the signals include fluctuations in pulse height and baseline. Analysis of actual data revealed that individual means of low and high frequency components of PRV showed good agreement with those of HRV (intraclass correlation coefficient, 0.997 and 0.981, respectively). Conclusions: The PFDM of pulse wave signal provides a reliable assessment of PRV. Given the popularity of pulse wave equipments, PFDM may open new ways to the studies of long-term assessment of cardiovascular variability and dynamics.
UR - http://www.scopus.com/inward/record.url?scp=27744434850&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=27744434850&partnerID=8YFLogxK
U2 - 10.1186/1475-925X-4-62
DO - 10.1186/1475-925X-4-62
M3 - Article
C2 - 16259639
AN - SCOPUS:27744434850
VL - 4
JO - BioMedical Engineering Online
JF - BioMedical Engineering Online
SN - 1475-925X
M1 - 62
ER -