Assessment of MRi findings and clinical symptoms in patients with temporomandibular joint disorders

Risa Matsubara, Yoshinobu Yanagi, Kazuhiro Oki, Miki Hisatomi, Karina C.P. Santos, Babatunde O. Bamgbose, Mariko Fujita, Shunsuke Okada, Shougo Minagi, Jun-Ichi Asaumi

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Objectives: To investigate the correlations among various temporomandibular joint (TMJ) findings on MRI and the relationships between MRI findings and symptoms. Methods: 425 patients (850 TMJs) with temporomandibular joint disorders (TMDs) who underwent MRI were enrolled. Oblique sagittal proton density-weighted and T2 weighted images in open- and closed-mouth positions were evaluated. MRI findings included disc configuration, disc position, condylar morphology, bone marrow pattern, and joint effusion. Symptoms included TMJ pain, TMJ noise, and limitation of mouth opening. For statistical analyses, Spearman's rank correlation coefficient and logistic regression analysis were applied. Results: Folded disc, disc displacement without reduction (DDWOR), and osteophytes had significant negative correlations with other normal MRI findings (p < 0.01). DDWOR and marrow edema were associated with TMJ pain. Conversely, osteophytes [odds ratio (OR): 0.52; 95% CI (0.30-0.90)] and combination-type condylar degeneration [OR: 0.45; 95% CI (0.24-0.83)] were associated with decreased risk of TMJ pain. Condylar flattening was positively associated with TMJ noise [OR: 5.25; 95% CI (1.44-19.07)] and negatively associated with limitation of mouth opening [OR: 0.34; 95% CI (0.11-0.99)]. High-grade joint effusion was significantly associated with TMJ pain and noise. conclusions: DDWOR and high-grade joint effusion (an indicator of inflammation in the articular cavity) were associated with TMD symptoms. This finding suggests that treatment strategy for DDWOR and decreasing inflammation might lessen clinical TMD symptoms. Condylar degeneration was not associated with indicators of inflammation or TMJ symptoms. These results suggest that patients with TMD symptoms should undergo initial MRI to allow rapid selection of appropriate therapies.

Original languageEnglish
Article number20170412
JournalDentomaxillofacial Radiology
Volume47
Issue number4
DOIs
Publication statusPublished - Jan 1 2018

Fingerprint

Temporomandibular Joint Disorders
Temporomandibular Joint
Arthralgia
Joints
Odds Ratio
Mouth
Noise
Osteophyte
Inflammation
Bone Marrow
Nonparametric Statistics
Protons
Edema
Logistic Models
Regression Analysis

Keywords

  • Analysis
  • Magnetic resonance imaging (MRI)
  • Symptoms
  • Temporomandibular joint
  • Temporomandibular joint disorder

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Radiology Nuclear Medicine and imaging
  • Dentistry(all)

Cite this

@article{80061b04a61f4f38849590cb3cb5ce10,
title = "Assessment of MRi findings and clinical symptoms in patients with temporomandibular joint disorders",
abstract = "Objectives: To investigate the correlations among various temporomandibular joint (TMJ) findings on MRI and the relationships between MRI findings and symptoms. Methods: 425 patients (850 TMJs) with temporomandibular joint disorders (TMDs) who underwent MRI were enrolled. Oblique sagittal proton density-weighted and T2 weighted images in open- and closed-mouth positions were evaluated. MRI findings included disc configuration, disc position, condylar morphology, bone marrow pattern, and joint effusion. Symptoms included TMJ pain, TMJ noise, and limitation of mouth opening. For statistical analyses, Spearman's rank correlation coefficient and logistic regression analysis were applied. Results: Folded disc, disc displacement without reduction (DDWOR), and osteophytes had significant negative correlations with other normal MRI findings (p < 0.01). DDWOR and marrow edema were associated with TMJ pain. Conversely, osteophytes [odds ratio (OR): 0.52; 95{\%} CI (0.30-0.90)] and combination-type condylar degeneration [OR: 0.45; 95{\%} CI (0.24-0.83)] were associated with decreased risk of TMJ pain. Condylar flattening was positively associated with TMJ noise [OR: 5.25; 95{\%} CI (1.44-19.07)] and negatively associated with limitation of mouth opening [OR: 0.34; 95{\%} CI (0.11-0.99)]. High-grade joint effusion was significantly associated with TMJ pain and noise. conclusions: DDWOR and high-grade joint effusion (an indicator of inflammation in the articular cavity) were associated with TMD symptoms. This finding suggests that treatment strategy for DDWOR and decreasing inflammation might lessen clinical TMD symptoms. Condylar degeneration was not associated with indicators of inflammation or TMJ symptoms. These results suggest that patients with TMD symptoms should undergo initial MRI to allow rapid selection of appropriate therapies.",
keywords = "Analysis, Magnetic resonance imaging (MRI), Symptoms, Temporomandibular joint, Temporomandibular joint disorder",
author = "Risa Matsubara and Yoshinobu Yanagi and Kazuhiro Oki and Miki Hisatomi and Santos, {Karina C.P.} and Bamgbose, {Babatunde O.} and Mariko Fujita and Shunsuke Okada and Shougo Minagi and Jun-Ichi Asaumi",
year = "2018",
month = "1",
day = "1",
doi = "10.1259/dmfr.20170412",
language = "English",
volume = "47",
journal = "Dentomaxillofacial Radiology",
issn = "0250-832X",
publisher = "British Institute of Radiology",
number = "4",

}

TY - JOUR

T1 - Assessment of MRi findings and clinical symptoms in patients with temporomandibular joint disorders

AU - Matsubara, Risa

AU - Yanagi, Yoshinobu

AU - Oki, Kazuhiro

AU - Hisatomi, Miki

AU - Santos, Karina C.P.

AU - Bamgbose, Babatunde O.

AU - Fujita, Mariko

AU - Okada, Shunsuke

AU - Minagi, Shougo

AU - Asaumi, Jun-Ichi

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Objectives: To investigate the correlations among various temporomandibular joint (TMJ) findings on MRI and the relationships between MRI findings and symptoms. Methods: 425 patients (850 TMJs) with temporomandibular joint disorders (TMDs) who underwent MRI were enrolled. Oblique sagittal proton density-weighted and T2 weighted images in open- and closed-mouth positions were evaluated. MRI findings included disc configuration, disc position, condylar morphology, bone marrow pattern, and joint effusion. Symptoms included TMJ pain, TMJ noise, and limitation of mouth opening. For statistical analyses, Spearman's rank correlation coefficient and logistic regression analysis were applied. Results: Folded disc, disc displacement without reduction (DDWOR), and osteophytes had significant negative correlations with other normal MRI findings (p < 0.01). DDWOR and marrow edema were associated with TMJ pain. Conversely, osteophytes [odds ratio (OR): 0.52; 95% CI (0.30-0.90)] and combination-type condylar degeneration [OR: 0.45; 95% CI (0.24-0.83)] were associated with decreased risk of TMJ pain. Condylar flattening was positively associated with TMJ noise [OR: 5.25; 95% CI (1.44-19.07)] and negatively associated with limitation of mouth opening [OR: 0.34; 95% CI (0.11-0.99)]. High-grade joint effusion was significantly associated with TMJ pain and noise. conclusions: DDWOR and high-grade joint effusion (an indicator of inflammation in the articular cavity) were associated with TMD symptoms. This finding suggests that treatment strategy for DDWOR and decreasing inflammation might lessen clinical TMD symptoms. Condylar degeneration was not associated with indicators of inflammation or TMJ symptoms. These results suggest that patients with TMD symptoms should undergo initial MRI to allow rapid selection of appropriate therapies.

AB - Objectives: To investigate the correlations among various temporomandibular joint (TMJ) findings on MRI and the relationships between MRI findings and symptoms. Methods: 425 patients (850 TMJs) with temporomandibular joint disorders (TMDs) who underwent MRI were enrolled. Oblique sagittal proton density-weighted and T2 weighted images in open- and closed-mouth positions were evaluated. MRI findings included disc configuration, disc position, condylar morphology, bone marrow pattern, and joint effusion. Symptoms included TMJ pain, TMJ noise, and limitation of mouth opening. For statistical analyses, Spearman's rank correlation coefficient and logistic regression analysis were applied. Results: Folded disc, disc displacement without reduction (DDWOR), and osteophytes had significant negative correlations with other normal MRI findings (p < 0.01). DDWOR and marrow edema were associated with TMJ pain. Conversely, osteophytes [odds ratio (OR): 0.52; 95% CI (0.30-0.90)] and combination-type condylar degeneration [OR: 0.45; 95% CI (0.24-0.83)] were associated with decreased risk of TMJ pain. Condylar flattening was positively associated with TMJ noise [OR: 5.25; 95% CI (1.44-19.07)] and negatively associated with limitation of mouth opening [OR: 0.34; 95% CI (0.11-0.99)]. High-grade joint effusion was significantly associated with TMJ pain and noise. conclusions: DDWOR and high-grade joint effusion (an indicator of inflammation in the articular cavity) were associated with TMD symptoms. This finding suggests that treatment strategy for DDWOR and decreasing inflammation might lessen clinical TMD symptoms. Condylar degeneration was not associated with indicators of inflammation or TMJ symptoms. These results suggest that patients with TMD symptoms should undergo initial MRI to allow rapid selection of appropriate therapies.

KW - Analysis

KW - Magnetic resonance imaging (MRI)

KW - Symptoms

KW - Temporomandibular joint

KW - Temporomandibular joint disorder

UR - http://www.scopus.com/inward/record.url?scp=85046155821&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85046155821&partnerID=8YFLogxK

U2 - 10.1259/dmfr.20170412

DO - 10.1259/dmfr.20170412

M3 - Article

VL - 47

JO - Dentomaxillofacial Radiology

JF - Dentomaxillofacial Radiology

SN - 0250-832X

IS - 4

M1 - 20170412

ER -