Assessment of medications in patients with tako-tsubo cardiomyopathy

Satoshi Kurisu, Ichiro Inoue, Takuji Kawagoe, Masaharu Ishihara, Yuji Shimatani, Yasuharu Nakama, Tatsuya Maruhashi, Eisuke Kagawa, Kazuoki Dai, Junichi Matsushita, Toshiyuki Aokage, Hiroki Ikenaga

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Background: Tako-tsubo cardiomyopathy has been gradually recognized worldwide. However, medications for the prevention remain not to be investigated in part because the precise mechanism is unclear. We sought to examine medications before the onset of tako-tsubo cardiomyopathy, and to prove the limitation of these medications for the prevention. Methods and results: This study consisted of 21 patients with tako-tsubo cardiomyopathy who received one or more medications for hypertension or suspected angina pectoris. Each patient was assessed with history, medications, coronary angiography and left ventriculography. All patients but 1 were female, and age ranged 41 to 87 years (73 ± 11 years). Twelve patients received calcium channel blockers, 7 patients received nitrates, and one patient received beta blocker. Three patients received angiotensin coverting enzyme inhibitors, and 4 patients received angiotensin II receptor blockers. One patient died of serious pneumonia, but there was no patient who died of tako-tsubo cardiomyopathy itself. During the 3 year follow-up, one patient receiving angiotensin receptor blocker had the recurrence of tako-tsubo cardiomyopathy due to recurrent epileptic seizure. Conclusions: Tako-tsubo cardiomyopathy can occur despite treatment with calcium channel blockers, nitrates or beta-blockers, suggesting limitation of these medications to prevent tako-tsubo cardiomyopathy.

Original languageEnglish
JournalInternational Journal of Cardiology
Volume134
Issue number3
DOIs
Publication statusPublished - May 29 2009
Externally publishedYes

Fingerprint

Takotsubo Cardiomyopathy
Angiotensin Receptor Antagonists
Calcium Channel Blockers
Nitrates
Angiotensins
Angina Pectoris
Enzyme Inhibitors
Coronary Angiography
Epilepsy
Pneumonia
History

Keywords

  • Medication
  • Prevention
  • Tako-tsubo

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Kurisu, S., Inoue, I., Kawagoe, T., Ishihara, M., Shimatani, Y., Nakama, Y., ... Ikenaga, H. (2009). Assessment of medications in patients with tako-tsubo cardiomyopathy. International Journal of Cardiology, 134(3). https://doi.org/10.1016/j.ijcard.2008.01.026

Assessment of medications in patients with tako-tsubo cardiomyopathy. / Kurisu, Satoshi; Inoue, Ichiro; Kawagoe, Takuji; Ishihara, Masaharu; Shimatani, Yuji; Nakama, Yasuharu; Maruhashi, Tatsuya; Kagawa, Eisuke; Dai, Kazuoki; Matsushita, Junichi; Aokage, Toshiyuki; Ikenaga, Hiroki.

In: International Journal of Cardiology, Vol. 134, No. 3, 29.05.2009.

Research output: Contribution to journalArticle

Kurisu, S, Inoue, I, Kawagoe, T, Ishihara, M, Shimatani, Y, Nakama, Y, Maruhashi, T, Kagawa, E, Dai, K, Matsushita, J, Aokage, T & Ikenaga, H 2009, 'Assessment of medications in patients with tako-tsubo cardiomyopathy', International Journal of Cardiology, vol. 134, no. 3. https://doi.org/10.1016/j.ijcard.2008.01.026
Kurisu, Satoshi ; Inoue, Ichiro ; Kawagoe, Takuji ; Ishihara, Masaharu ; Shimatani, Yuji ; Nakama, Yasuharu ; Maruhashi, Tatsuya ; Kagawa, Eisuke ; Dai, Kazuoki ; Matsushita, Junichi ; Aokage, Toshiyuki ; Ikenaga, Hiroki. / Assessment of medications in patients with tako-tsubo cardiomyopathy. In: International Journal of Cardiology. 2009 ; Vol. 134, No. 3.
@article{381737c27e524468a80b4308f0073652,
title = "Assessment of medications in patients with tako-tsubo cardiomyopathy",
abstract = "Background: Tako-tsubo cardiomyopathy has been gradually recognized worldwide. However, medications for the prevention remain not to be investigated in part because the precise mechanism is unclear. We sought to examine medications before the onset of tako-tsubo cardiomyopathy, and to prove the limitation of these medications for the prevention. Methods and results: This study consisted of 21 patients with tako-tsubo cardiomyopathy who received one or more medications for hypertension or suspected angina pectoris. Each patient was assessed with history, medications, coronary angiography and left ventriculography. All patients but 1 were female, and age ranged 41 to 87 years (73 ± 11 years). Twelve patients received calcium channel blockers, 7 patients received nitrates, and one patient received beta blocker. Three patients received angiotensin coverting enzyme inhibitors, and 4 patients received angiotensin II receptor blockers. One patient died of serious pneumonia, but there was no patient who died of tako-tsubo cardiomyopathy itself. During the 3 year follow-up, one patient receiving angiotensin receptor blocker had the recurrence of tako-tsubo cardiomyopathy due to recurrent epileptic seizure. Conclusions: Tako-tsubo cardiomyopathy can occur despite treatment with calcium channel blockers, nitrates or beta-blockers, suggesting limitation of these medications to prevent tako-tsubo cardiomyopathy.",
keywords = "Medication, Prevention, Tako-tsubo",
author = "Satoshi Kurisu and Ichiro Inoue and Takuji Kawagoe and Masaharu Ishihara and Yuji Shimatani and Yasuharu Nakama and Tatsuya Maruhashi and Eisuke Kagawa and Kazuoki Dai and Junichi Matsushita and Toshiyuki Aokage and Hiroki Ikenaga",
year = "2009",
month = "5",
day = "29",
doi = "10.1016/j.ijcard.2008.01.026",
language = "English",
volume = "134",
journal = "International Journal of Cardiology",
issn = "0167-5273",
publisher = "Elsevier Ireland Ltd",
number = "3",

}

TY - JOUR

T1 - Assessment of medications in patients with tako-tsubo cardiomyopathy

AU - Kurisu, Satoshi

AU - Inoue, Ichiro

AU - Kawagoe, Takuji

AU - Ishihara, Masaharu

AU - Shimatani, Yuji

AU - Nakama, Yasuharu

AU - Maruhashi, Tatsuya

AU - Kagawa, Eisuke

AU - Dai, Kazuoki

AU - Matsushita, Junichi

AU - Aokage, Toshiyuki

AU - Ikenaga, Hiroki

PY - 2009/5/29

Y1 - 2009/5/29

N2 - Background: Tako-tsubo cardiomyopathy has been gradually recognized worldwide. However, medications for the prevention remain not to be investigated in part because the precise mechanism is unclear. We sought to examine medications before the onset of tako-tsubo cardiomyopathy, and to prove the limitation of these medications for the prevention. Methods and results: This study consisted of 21 patients with tako-tsubo cardiomyopathy who received one or more medications for hypertension or suspected angina pectoris. Each patient was assessed with history, medications, coronary angiography and left ventriculography. All patients but 1 were female, and age ranged 41 to 87 years (73 ± 11 years). Twelve patients received calcium channel blockers, 7 patients received nitrates, and one patient received beta blocker. Three patients received angiotensin coverting enzyme inhibitors, and 4 patients received angiotensin II receptor blockers. One patient died of serious pneumonia, but there was no patient who died of tako-tsubo cardiomyopathy itself. During the 3 year follow-up, one patient receiving angiotensin receptor blocker had the recurrence of tako-tsubo cardiomyopathy due to recurrent epileptic seizure. Conclusions: Tako-tsubo cardiomyopathy can occur despite treatment with calcium channel blockers, nitrates or beta-blockers, suggesting limitation of these medications to prevent tako-tsubo cardiomyopathy.

AB - Background: Tako-tsubo cardiomyopathy has been gradually recognized worldwide. However, medications for the prevention remain not to be investigated in part because the precise mechanism is unclear. We sought to examine medications before the onset of tako-tsubo cardiomyopathy, and to prove the limitation of these medications for the prevention. Methods and results: This study consisted of 21 patients with tako-tsubo cardiomyopathy who received one or more medications for hypertension or suspected angina pectoris. Each patient was assessed with history, medications, coronary angiography and left ventriculography. All patients but 1 were female, and age ranged 41 to 87 years (73 ± 11 years). Twelve patients received calcium channel blockers, 7 patients received nitrates, and one patient received beta blocker. Three patients received angiotensin coverting enzyme inhibitors, and 4 patients received angiotensin II receptor blockers. One patient died of serious pneumonia, but there was no patient who died of tako-tsubo cardiomyopathy itself. During the 3 year follow-up, one patient receiving angiotensin receptor blocker had the recurrence of tako-tsubo cardiomyopathy due to recurrent epileptic seizure. Conclusions: Tako-tsubo cardiomyopathy can occur despite treatment with calcium channel blockers, nitrates or beta-blockers, suggesting limitation of these medications to prevent tako-tsubo cardiomyopathy.

KW - Medication

KW - Prevention

KW - Tako-tsubo

UR - http://www.scopus.com/inward/record.url?scp=67349105039&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=67349105039&partnerID=8YFLogxK

U2 - 10.1016/j.ijcard.2008.01.026

DO - 10.1016/j.ijcard.2008.01.026

M3 - Article

C2 - 18499288

AN - SCOPUS:67349105039

VL - 134

JO - International Journal of Cardiology

JF - International Journal of Cardiology

SN - 0167-5273

IS - 3

ER -