[Archives of "comprehensive approach on asbestos-related diseases" supported by the "special coordination funds for promoting science and technology (H18-1-3-3-1)"-- overview of group research project, care and specimen registration, cellular characteristics of mesothelioma and immunological effects of asbestos].

Takemi Otsuki, Takashi Nakano, Seiki Hasegawa, Morihito Okada, Tohru Tsujimura, Yoshitaka Sekido, Shinya Toyokuni, Hiroshi Nishimoto, Kazuya Fukuoka, Fumihiro Tanaka, Naoko Kumagai, Megumi Maeda, Yasumitsu Nishimura

Research output: Contribution to journalArticle

Abstract

The research project entitled "Comprehensive approach on asbestos-related diseases" supported by the "Special Coordination Funds for Promoting Science and Technology (H18-1-3-3-1)" began in 2006 and was completed at the end of the Japanese fiscal year of 2010. This project included four parts; (1) malignant mesothelioma (MM) cases and specimen registration, (2) development of procedures for the early diagnosis of MM, (3) commencement of clinical investigations including multimodal approaches, and (4) basic research comprising three components; (i) cellular and molecular characterization of mesothelioma cells, (ii) immunological effects of asbestos, and (iii) elucidation of asbestos-induced carcinogenesis using animal models. In this special issue of the Japanese Journal of Hygiene, we briefly introduce the achievements of our project. The second and third parts and the third component of the fourth part are described in other manuscripts written by Professors Fukuoka, Hasegawa, and Toyokuni. In this manuscript, we introduce a brief summary of the first part "MM cases and specimen registration", the first component of the fourth part "Cellular and molecular characterization of mesothelioma cells" and the second component of the fourth part "Immunological effects of asbestos". In addition, a previous special issue presented by the Study Group of Fibrous and Particulate Substances (SGFPS) (chaired by Professor Otsuki, Kawasaki Medical School, Japan) for the Japanese Society of Hygiene and published in Environmental Health and Preventive Medicine Volume 13, 2008, included reviews of the aforementioned first component of the fourth part of the project. Taken together, our project led medical investigations regarding asbestos and MM progress and contributed towards the care and examination of patients with asbestos-related diseases during these five years. Further investigations are required to facilitate the development of preventive measures and the cure of asbestos-related diseases, particularly in Japan, where asbestos-related diseases are predicted to increase in the next 10 to 20 years.

Original languageEnglish
Pages (from-to)543-552
Number of pages10
JournalJapanese Journal of Hygiene
Volume66
Issue number3
DOIs
Publication statusPublished - May 2011
Externally publishedYes

Fingerprint

Asbestos
Mesothelioma
Financial Management
Technology
Research
Hygiene
Japan
Environmental Medicine
Preventive Medicine
Environmental Health
Manuscripts
Cellular Structures
Medical Schools
Early Diagnosis
Patient Care
Carcinogenesis
Animal Models
Malignant Mesothelioma

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

Cite this

[Archives of "comprehensive approach on asbestos-related diseases" supported by the "special coordination funds for promoting science and technology (H18-1-3-3-1)"-- overview of group research project, care and specimen registration, cellular characteristics of mesothelioma and immunological effects of asbestos]. / Otsuki, Takemi; Nakano, Takashi; Hasegawa, Seiki; Okada, Morihito; Tsujimura, Tohru; Sekido, Yoshitaka; Toyokuni, Shinya; Nishimoto, Hiroshi; Fukuoka, Kazuya; Tanaka, Fumihiro; Kumagai, Naoko; Maeda, Megumi; Nishimura, Yasumitsu.

In: Japanese Journal of Hygiene, Vol. 66, No. 3, 05.2011, p. 543-552.

Research output: Contribution to journalArticle

Otsuki, Takemi ; Nakano, Takashi ; Hasegawa, Seiki ; Okada, Morihito ; Tsujimura, Tohru ; Sekido, Yoshitaka ; Toyokuni, Shinya ; Nishimoto, Hiroshi ; Fukuoka, Kazuya ; Tanaka, Fumihiro ; Kumagai, Naoko ; Maeda, Megumi ; Nishimura, Yasumitsu. / [Archives of "comprehensive approach on asbestos-related diseases" supported by the "special coordination funds for promoting science and technology (H18-1-3-3-1)"-- overview of group research project, care and specimen registration, cellular characteristics of mesothelioma and immunological effects of asbestos]. In: Japanese Journal of Hygiene. 2011 ; Vol. 66, No. 3. pp. 543-552.
@article{82458fc74b2e44a2bd3357facd93c70f,
title = "[Archives of {"}comprehensive approach on asbestos-related diseases{"} supported by the {"}special coordination funds for promoting science and technology (H18-1-3-3-1){"}-- overview of group research project, care and specimen registration, cellular characteristics of mesothelioma and immunological effects of asbestos].",
abstract = "The research project entitled {"}Comprehensive approach on asbestos-related diseases{"} supported by the {"}Special Coordination Funds for Promoting Science and Technology (H18-1-3-3-1){"} began in 2006 and was completed at the end of the Japanese fiscal year of 2010. This project included four parts; (1) malignant mesothelioma (MM) cases and specimen registration, (2) development of procedures for the early diagnosis of MM, (3) commencement of clinical investigations including multimodal approaches, and (4) basic research comprising three components; (i) cellular and molecular characterization of mesothelioma cells, (ii) immunological effects of asbestos, and (iii) elucidation of asbestos-induced carcinogenesis using animal models. In this special issue of the Japanese Journal of Hygiene, we briefly introduce the achievements of our project. The second and third parts and the third component of the fourth part are described in other manuscripts written by Professors Fukuoka, Hasegawa, and Toyokuni. In this manuscript, we introduce a brief summary of the first part {"}MM cases and specimen registration{"}, the first component of the fourth part {"}Cellular and molecular characterization of mesothelioma cells{"} and the second component of the fourth part {"}Immunological effects of asbestos{"}. In addition, a previous special issue presented by the Study Group of Fibrous and Particulate Substances (SGFPS) (chaired by Professor Otsuki, Kawasaki Medical School, Japan) for the Japanese Society of Hygiene and published in Environmental Health and Preventive Medicine Volume 13, 2008, included reviews of the aforementioned first component of the fourth part of the project. Taken together, our project led medical investigations regarding asbestos and MM progress and contributed towards the care and examination of patients with asbestos-related diseases during these five years. Further investigations are required to facilitate the development of preventive measures and the cure of asbestos-related diseases, particularly in Japan, where asbestos-related diseases are predicted to increase in the next 10 to 20 years.",
author = "Takemi Otsuki and Takashi Nakano and Seiki Hasegawa and Morihito Okada and Tohru Tsujimura and Yoshitaka Sekido and Shinya Toyokuni and Hiroshi Nishimoto and Kazuya Fukuoka and Fumihiro Tanaka and Naoko Kumagai and Megumi Maeda and Yasumitsu Nishimura",
year = "2011",
month = "5",
doi = "10.1265/jjh.66.543",
language = "English",
volume = "66",
pages = "543--552",
journal = "Japanese Journal of Hygiene",
issn = "0021-5082",
publisher = "Japanese Society for Hygiene",
number = "3",

}

TY - JOUR

T1 - [Archives of "comprehensive approach on asbestos-related diseases" supported by the "special coordination funds for promoting science and technology (H18-1-3-3-1)"-- overview of group research project, care and specimen registration, cellular characteristics of mesothelioma and immunological effects of asbestos].

AU - Otsuki, Takemi

AU - Nakano, Takashi

AU - Hasegawa, Seiki

AU - Okada, Morihito

AU - Tsujimura, Tohru

AU - Sekido, Yoshitaka

AU - Toyokuni, Shinya

AU - Nishimoto, Hiroshi

AU - Fukuoka, Kazuya

AU - Tanaka, Fumihiro

AU - Kumagai, Naoko

AU - Maeda, Megumi

AU - Nishimura, Yasumitsu

PY - 2011/5

Y1 - 2011/5

N2 - The research project entitled "Comprehensive approach on asbestos-related diseases" supported by the "Special Coordination Funds for Promoting Science and Technology (H18-1-3-3-1)" began in 2006 and was completed at the end of the Japanese fiscal year of 2010. This project included four parts; (1) malignant mesothelioma (MM) cases and specimen registration, (2) development of procedures for the early diagnosis of MM, (3) commencement of clinical investigations including multimodal approaches, and (4) basic research comprising three components; (i) cellular and molecular characterization of mesothelioma cells, (ii) immunological effects of asbestos, and (iii) elucidation of asbestos-induced carcinogenesis using animal models. In this special issue of the Japanese Journal of Hygiene, we briefly introduce the achievements of our project. The second and third parts and the third component of the fourth part are described in other manuscripts written by Professors Fukuoka, Hasegawa, and Toyokuni. In this manuscript, we introduce a brief summary of the first part "MM cases and specimen registration", the first component of the fourth part "Cellular and molecular characterization of mesothelioma cells" and the second component of the fourth part "Immunological effects of asbestos". In addition, a previous special issue presented by the Study Group of Fibrous and Particulate Substances (SGFPS) (chaired by Professor Otsuki, Kawasaki Medical School, Japan) for the Japanese Society of Hygiene and published in Environmental Health and Preventive Medicine Volume 13, 2008, included reviews of the aforementioned first component of the fourth part of the project. Taken together, our project led medical investigations regarding asbestos and MM progress and contributed towards the care and examination of patients with asbestos-related diseases during these five years. Further investigations are required to facilitate the development of preventive measures and the cure of asbestos-related diseases, particularly in Japan, where asbestos-related diseases are predicted to increase in the next 10 to 20 years.

AB - The research project entitled "Comprehensive approach on asbestos-related diseases" supported by the "Special Coordination Funds for Promoting Science and Technology (H18-1-3-3-1)" began in 2006 and was completed at the end of the Japanese fiscal year of 2010. This project included four parts; (1) malignant mesothelioma (MM) cases and specimen registration, (2) development of procedures for the early diagnosis of MM, (3) commencement of clinical investigations including multimodal approaches, and (4) basic research comprising three components; (i) cellular and molecular characterization of mesothelioma cells, (ii) immunological effects of asbestos, and (iii) elucidation of asbestos-induced carcinogenesis using animal models. In this special issue of the Japanese Journal of Hygiene, we briefly introduce the achievements of our project. The second and third parts and the third component of the fourth part are described in other manuscripts written by Professors Fukuoka, Hasegawa, and Toyokuni. In this manuscript, we introduce a brief summary of the first part "MM cases and specimen registration", the first component of the fourth part "Cellular and molecular characterization of mesothelioma cells" and the second component of the fourth part "Immunological effects of asbestos". In addition, a previous special issue presented by the Study Group of Fibrous and Particulate Substances (SGFPS) (chaired by Professor Otsuki, Kawasaki Medical School, Japan) for the Japanese Society of Hygiene and published in Environmental Health and Preventive Medicine Volume 13, 2008, included reviews of the aforementioned first component of the fourth part of the project. Taken together, our project led medical investigations regarding asbestos and MM progress and contributed towards the care and examination of patients with asbestos-related diseases during these five years. Further investigations are required to facilitate the development of preventive measures and the cure of asbestos-related diseases, particularly in Japan, where asbestos-related diseases are predicted to increase in the next 10 to 20 years.

UR - http://www.scopus.com/inward/record.url?scp=79961150389&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79961150389&partnerID=8YFLogxK

U2 - 10.1265/jjh.66.543

DO - 10.1265/jjh.66.543

M3 - Article

C2 - 21701085

AN - SCOPUS:79961150389

VL - 66

SP - 543

EP - 552

JO - Japanese Journal of Hygiene

JF - Japanese Journal of Hygiene

SN - 0021-5082

IS - 3

ER -