Application of soft lithography to mechanobiology

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Mechanobiology is indispensable to all living creatures ranging from bacteria to human beings because every living thing continually experiences mechanical stimuli, not only exogenous but also endogenous, and responds appropriately to these stimuli. At the cellular level, there are three major mechanical stresses, such as, stretch, shear stress and pressure (Fig. 1A). We have been intensively investigating systems to apply these mechanical environments to cells. Analysis of these responses is critical to understand the mechanisms and regulation of diverse physiological processes such as arterial and regulation, sensory perception, muscle development, and so on. Therefore, to study mechanobiology, we employed the polydimethysiloxane (PDMS, Fig. 1B) based technology, which is called soft lithography. In this article, I am going to focus on 3 major utilizations such as stretch chambers, microcontact printing, and microchannel.

Original languageEnglish
Title of host publicationProceedings of the 2005 International Symposium on Micro-NanoMechatronics and Human Science, Eighth Symposium on Micro- and Nano-Mechatronics for Information-Based Society - The 21st Century COE Progr
Pages245-250
Number of pages6
DOIs
Publication statusPublished - Dec 1 2005
Event2005 International Symposium on Micro-NanoMechatronics and Human Science, Eighth Symposium on Micro- and Nano-Mechatronics for Information-Based Society - The 21st Century COE Program - Nagayo, Japan
Duration: Nov 7 2005Nov 9 2005

Publication series

NameProceedings of the 2005 International Symposium on Micro-NanoMechatronics and Human Science, Eighth Symposium on Micro- and Nano-Mechatronics for Information-Based Society - The 21st Century COE Progr
Volume2005

Other

Other2005 International Symposium on Micro-NanoMechatronics and Human Science, Eighth Symposium on Micro- and Nano-Mechatronics for Information-Based Society - The 21st Century COE Program
CountryJapan
CityNagayo
Period11/7/0511/9/05

ASJC Scopus subject areas

  • Engineering(all)

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    Naruse, K. (2005). Application of soft lithography to mechanobiology. In Proceedings of the 2005 International Symposium on Micro-NanoMechatronics and Human Science, Eighth Symposium on Micro- and Nano-Mechatronics for Information-Based Society - The 21st Century COE Progr (pp. 245-250). [1589998] (Proceedings of the 2005 International Symposium on Micro-NanoMechatronics and Human Science, Eighth Symposium on Micro- and Nano-Mechatronics for Information-Based Society - The 21st Century COE Progr; Vol. 2005). https://doi.org/10.1109/MHS.2005.1589998