Abstract
Background/Aims: The aim of this study is to elucidate the effectiveness of radiofrequency ablation (RFA) for the treatment of metastatic liver cancers. Methodology: From 74 patients with metastatic liver cancers treated by RFA, 40 patients including 23 colon cancer who had received curative resection of the primary tumor were analyzed. Results: Recurrence of the tumor was observed in 29 (72.5%) patients. The most prevalent site of recurrence was the liver in both colon cancer (10/15, 66.7%) and non-colon cancer patients (12/14, 85.7%). Among the recurrence in the liver, the rate of intrahepatic distant recurrence (recurrence outside of the RFA-treated segment) was high in both colon cancer (55.6%) and non-colon cancer patients (69.0%). Local recurrence (recurrence at the RFA-treated segment) rate was low (32.6% and 32.9%, respectively) and none of single tumor less than 2cm in diameter showed local recurrence. The intrahepatic recurrence was single in 67.6% of the patients and 59.1% of the patients were re-treated by RFA. Conclusions: RFA is a less-invasive method for the treatment of metastatic liver tumors and can be performed repetitively. Although the rate of intra-hepatic distant recurrence and extra-hepatic recurrence was high, good local control can be achieved by RFA.
| Original language | English |
|---|---|
| Pages (from-to) | 117-120 |
| Number of pages | 4 |
| Journal | Hepato-Gastroenterology |
| Volume | 57 |
| Issue number | 97 |
| Publication status | Published - Jan 2010 |
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Keywords
- Liver neoplasm
- Metastasis
- Prognosis
- Therapeutics
ASJC Scopus subject areas
- Gastroenterology
- Hepatology
Cite this
Application of radiofrequency ablation for the treatment of metastatic liver cancers. / Nouso, Kazuhiro; Kobayashi, Yoshiyuki; Nakamura, Shinichiro; Uematsu, Shuji; Shiraga, Kunihiro; Iwadou, Shouta; Araki, Yasuyuki; Taniguchi, Hideaki; Tanaka, Hironori; Toshikuni, Nobuyuki; Kaneyoshi, Toshihiko; Ikeda, Hiroshi; Fujioka, Shinichi; Osawa, Toshiya; Iwasaki, Yoshiaki; Shiraha, Hidenori; Yamamoto, Kazuhide.
In: Hepato-Gastroenterology, Vol. 57, No. 97, 01.2010, p. 117-120.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Application of radiofrequency ablation for the treatment of metastatic liver cancers
AU - Nouso, Kazuhiro
AU - Kobayashi, Yoshiyuki
AU - Nakamura, Shinichiro
AU - Uematsu, Shuji
AU - Shiraga, Kunihiro
AU - Iwadou, Shouta
AU - Araki, Yasuyuki
AU - Taniguchi, Hideaki
AU - Tanaka, Hironori
AU - Toshikuni, Nobuyuki
AU - Kaneyoshi, Toshihiko
AU - Ikeda, Hiroshi
AU - Fujioka, Shinichi
AU - Osawa, Toshiya
AU - Iwasaki, Yoshiaki
AU - Shiraha, Hidenori
AU - Yamamoto, Kazuhide
PY - 2010/1
Y1 - 2010/1
N2 - Background/Aims: The aim of this study is to elucidate the effectiveness of radiofrequency ablation (RFA) for the treatment of metastatic liver cancers. Methodology: From 74 patients with metastatic liver cancers treated by RFA, 40 patients including 23 colon cancer who had received curative resection of the primary tumor were analyzed. Results: Recurrence of the tumor was observed in 29 (72.5%) patients. The most prevalent site of recurrence was the liver in both colon cancer (10/15, 66.7%) and non-colon cancer patients (12/14, 85.7%). Among the recurrence in the liver, the rate of intrahepatic distant recurrence (recurrence outside of the RFA-treated segment) was high in both colon cancer (55.6%) and non-colon cancer patients (69.0%). Local recurrence (recurrence at the RFA-treated segment) rate was low (32.6% and 32.9%, respectively) and none of single tumor less than 2cm in diameter showed local recurrence. The intrahepatic recurrence was single in 67.6% of the patients and 59.1% of the patients were re-treated by RFA. Conclusions: RFA is a less-invasive method for the treatment of metastatic liver tumors and can be performed repetitively. Although the rate of intra-hepatic distant recurrence and extra-hepatic recurrence was high, good local control can be achieved by RFA.
AB - Background/Aims: The aim of this study is to elucidate the effectiveness of radiofrequency ablation (RFA) for the treatment of metastatic liver cancers. Methodology: From 74 patients with metastatic liver cancers treated by RFA, 40 patients including 23 colon cancer who had received curative resection of the primary tumor were analyzed. Results: Recurrence of the tumor was observed in 29 (72.5%) patients. The most prevalent site of recurrence was the liver in both colon cancer (10/15, 66.7%) and non-colon cancer patients (12/14, 85.7%). Among the recurrence in the liver, the rate of intrahepatic distant recurrence (recurrence outside of the RFA-treated segment) was high in both colon cancer (55.6%) and non-colon cancer patients (69.0%). Local recurrence (recurrence at the RFA-treated segment) rate was low (32.6% and 32.9%, respectively) and none of single tumor less than 2cm in diameter showed local recurrence. The intrahepatic recurrence was single in 67.6% of the patients and 59.1% of the patients were re-treated by RFA. Conclusions: RFA is a less-invasive method for the treatment of metastatic liver tumors and can be performed repetitively. Although the rate of intra-hepatic distant recurrence and extra-hepatic recurrence was high, good local control can be achieved by RFA.
KW - Liver neoplasm
KW - Metastasis
KW - Prognosis
KW - Therapeutics
UR - http://www.scopus.com/inward/record.url?scp=77952004723&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77952004723&partnerID=8YFLogxK
M3 - Article
C2 - 20422885
AN - SCOPUS:77952004723
VL - 57
SP - 117
EP - 120
JO - Acta hepato-splenologica
JF - Acta hepato-splenologica
SN - 0172-6390
IS - 97
ER -