Application of propranolol to the keratinized oral mucosa: Avoidance of first-pass elimination and the use of 1-dodecylazacycloheptan-2-one (azone) as an absorption enhancer of bioadhesive film-dosage form

Yuji Kurosaki, T. Takatori, M. Kitayama, T. Nakayama, T. Kimura

Research output: Contribution to journalArticle

18 Citations (Scopus)
Original languageEnglish
Pages (from-to)824-832
Number of pages9
JournalJournal of Pharmacobio-Dynamics
Volume11
Issue number12
Publication statusPublished - 1988

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Azepines
Cheek
Mesocricetus
Dosage Forms
Mouth Mucosa
Propranolol
Cricetinae
Biological Availability
Liver
Pharmaceutical Societies
laurocapram
In Vitro Techniques
hydroxypropylcellulose
Emulsions
Small Intestine
Japan

ASJC Scopus subject areas

  • Pharmacology

Cite this

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title = "Application of propranolol to the keratinized oral mucosa: Avoidance of first-pass elimination and the use of 1-dodecylazacycloheptan-2-one (azone) as an absorption enhancer of bioadhesive film-dosage form",
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AU - Takatori, T.

AU - Kitayama, M.

AU - Nakayama, T.

AU - Kimura, T.

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