Application of Hadamard transform to gas chromatography/nonresonant multiphoton ionization/time-of-flight mass spectrometry

Chao Chiang Cheng, Hung Wei Chang, Tomohiro Uchimura, Totaro Imasaka, Takashi Kaneta, Cheng Huang Lin

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

The technique of Hadamard transform was successfully coupled with GC/nonresonant multiphoton ionization/TOFMS, for the first time. 1,4-Dichlorobenzene and the fourth harmonic generation (266 nm) of a Nd:YAG laser were employed as a model sample and an ionization laser, respectively. A Hadamard-injector coupled with a capillary-based supersonic jet nozzle (capillary-injector) was also developed in this study. The Hadamard-injector was used to obtain the chromatogram, which was encoded by successive sample introduction based on Hadamard codes, and the capillary-injector was used for injection of GC-elutes into TOFMS. Compared with a conventional single injection method, the S/N ratios were substantially improved after inverse Hadamard transformation of the encoded chromatogram. Under optimized conditions, when Hadamard matrices of 103 and 255 were used, the S/N ratios of the signals for 1,4-dichlorobenzene (concentration level, 4 mg/1 mL ACN) were substantially improved to 4.1- and 6.6-fold, respectively, and those improvements are in good agreement with those obtained by theory (5.1- and 8.0-fold).

Original languageEnglish
Pages (from-to)626-630
Number of pages5
JournalJournal of Separation Science
Volume33
Issue number4-5
DOIs
Publication statusPublished - Mar 2010
Externally publishedYes

Fingerprint

Hadamard transforms
Gas chromatography
Ionization
Mass spectrometry
Hadamard matrices
Lasers
Harmonic generation
Nozzles
4-dichlorobenzene
3-hydroxy-5-estrane-17-carbonitrile

Keywords

  • 1,4-Dichlorobenzene
  • GC
  • Hadamard transform
  • Nonresonant multiphoton ionization
  • TOFMS

ASJC Scopus subject areas

  • Analytical Chemistry
  • Filtration and Separation

Cite this

Application of Hadamard transform to gas chromatography/nonresonant multiphoton ionization/time-of-flight mass spectrometry. / Cheng, Chao Chiang; Chang, Hung Wei; Uchimura, Tomohiro; Imasaka, Totaro; Kaneta, Takashi; Lin, Cheng Huang.

In: Journal of Separation Science, Vol. 33, No. 4-5, 03.2010, p. 626-630.

Research output: Contribution to journalArticle

Cheng, Chao Chiang ; Chang, Hung Wei ; Uchimura, Tomohiro ; Imasaka, Totaro ; Kaneta, Takashi ; Lin, Cheng Huang. / Application of Hadamard transform to gas chromatography/nonresonant multiphoton ionization/time-of-flight mass spectrometry. In: Journal of Separation Science. 2010 ; Vol. 33, No. 4-5. pp. 626-630.
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