Abstract
Three new kalihinane diterpenoids Δ9-kalihinol Y (1), 10-epikalihinol I (2) and 5,10-bisisothiocyanatokalihinol G (3) were isolated in the present study along with previously detected kalihinane diterpenoids kalihinol A (4), kalihinene (5) and 6-hydroxykalihinene (6) from the Okinawan marine sponge, Acanthella sp. Kalihinol A (4) was noted to possess remarkable in vitro antimalarial activity.
Original language | English |
---|---|
Pages (from-to) | 13467-13474 |
Number of pages | 8 |
Journal | Tetrahedron |
Volume | 54 |
Issue number | 44 |
DOIs | |
Publication status | Published - Oct 29 1998 |
Keywords
- Antimalarial compounds
- Marine metabolites
- Natural products
- Terpenes and terpenoids
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry