Antimalarial activities in vitro of homoprotoberberine derivatives against Plasmodium falciparum were examined. It has shown that 9-hydroxy- 2,3,10-trimethoxyhomoprotoberberine (10) was the most potent compound and the hydroxyl group at the C-9 position would play a significant role in exhibiting antimalarial activity and selective toxicity.
|Number of pages||4|
|Publication status||Published - Dec 31 1998|
ASJC Scopus subject areas
- Organic Chemistry