Antibacterial activity of polyphenol components in oolong tea extract against Streptococcus mutans

H. Sasaki, Michiyo Nakano, T. Tanaka, M. Maeda, M. Nakai, S. Hamada, T. Ooshima

Research output: Contribution to journalArticle

66 Citations (Scopus)

Abstract

The purpose of the present study was to determine the antibacterial activity of oolong tea extract on oral streptococci, including Streptococcus mutans and Streptococcus sobrinus, and to identify the response to its components. Antibacterial activity was found when the extract was added to S. mutans cells in chemically defined medium but not in complex broth media. Further, pre-treatment with bovine serum albumin reduced the antibacterial activity. The extract showed antibacterial activity against all of the oral streptococci examined, with the highest activity against S. mutans MT8148R. This activity was found to originate from a monomeric polyphenol-rich fraction, and it was stronger than that of pure polyphenols. Moreover, some combinations of monomeric polyphenols showed the highest level of antibacterial activity. These results suggest that the antibacterial activity of oolong tea extract is caused by a synergistic effect of monomeric polyphenols, which can easily bind to proteins.

Original languageEnglish
Pages (from-to)2-8
Number of pages7
JournalCaries Research
Volume38
Issue number1
DOIs
Publication statusPublished - 2004
Externally publishedYes

Fingerprint

Streptococcus mutans
Polyphenols
Tea
Streptococcus
Streptococcus sobrinus
Bovine Serum Albumin
Proteins

Keywords

  • Antibacterial activity
  • Oolong tea
  • Polyphenol
  • Streptococcus mutans
  • Synergistic effect

ASJC Scopus subject areas

  • Dentistry(all)

Cite this

Antibacterial activity of polyphenol components in oolong tea extract against Streptococcus mutans. / Sasaki, H.; Nakano, Michiyo; Tanaka, T.; Maeda, M.; Nakai, M.; Hamada, S.; Ooshima, T.

In: Caries Research, Vol. 38, No. 1, 2004, p. 2-8.

Research output: Contribution to journalArticle

Sasaki, H. ; Nakano, Michiyo ; Tanaka, T. ; Maeda, M. ; Nakai, M. ; Hamada, S. ; Ooshima, T. / Antibacterial activity of polyphenol components in oolong tea extract against Streptococcus mutans. In: Caries Research. 2004 ; Vol. 38, No. 1. pp. 2-8.
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