Anti-β2-glycoprotein I antibodies

A. Tsutsumi, K. Ichikawa, Eiji Matsuura, T. Koike

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

The relationship between presence of anti-β2-glycoprotein I autoantibodies (aβ2-GPI) and history of thrombosis is now widely known. However, differences in the methodology of aβ2-GPI detection have made the comparison of data from different laboratories extremely difficult. We discuss the significance of aβ2-GPI of the IgG, IgM and IgA isotypes, and our approach to developing an easier and more reproducible method for the detection of this autoantibody. In addition, we present data that shows that commercially available enzyme immunoassay plates differ regarding detectability of aβ2-GPI. Since the clinical significance of this heterogeneity is presently unclear, the set-up of the detection systems and interpretation of data need great care.

Original languageEnglish
JournalLupus
Volume7
Issue numberSUPPL. 2
Publication statusPublished - 1998

Fingerprint

Autoantibodies
Glycoproteins
Antibodies
Immunoenzyme Techniques
Information Systems
Immunoglobulin A
Immunoglobulin M
Thrombosis
Immunoglobulin G

Keywords

  • β-glycoprotein I
  • Anti-β-glycoprotein I
  • Enzyme immunoassay

ASJC Scopus subject areas

  • Immunology
  • Rheumatology

Cite this

Tsutsumi, A., Ichikawa, K., Matsuura, E., & Koike, T. (1998). Anti-β2-glycoprotein I antibodies. Lupus, 7(SUPPL. 2).

Anti-β2-glycoprotein I antibodies. / Tsutsumi, A.; Ichikawa, K.; Matsuura, Eiji; Koike, T.

In: Lupus, Vol. 7, No. SUPPL. 2, 1998.

Research output: Contribution to journalArticle

Tsutsumi, A, Ichikawa, K, Matsuura, E & Koike, T 1998, 'Anti-β2-glycoprotein I antibodies', Lupus, vol. 7, no. SUPPL. 2.
Tsutsumi A, Ichikawa K, Matsuura E, Koike T. Anti-β2-glycoprotein I antibodies. Lupus. 1998;7(SUPPL. 2).
Tsutsumi, A. ; Ichikawa, K. ; Matsuura, Eiji ; Koike, T. / Anti-β2-glycoprotein I antibodies. In: Lupus. 1998 ; Vol. 7, No. SUPPL. 2.
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