Abstract
Anisaldehyde (4-methoxybenzaldehyde), previously reported as a tyrosinase inhibitor, did not inhibit melanogenesis in cultured B16-F10 melanoma cells but rather enhanced it. This adverse effect of anisaldehyde was accompanied by melanocytotoxicity in a dose-dependent manner up to 2 mM. The melanin content per cell at 1 mM was increased 5-fold compared to control and morphological observations showed the deposition of melanin pigments. Anisaldehyde was also examined against cultured human A375 melanoma cells.
| Original language | English |
|---|---|
| Pages (from-to) | 143-149 |
| Number of pages | 7 |
| Journal | Zeitschrift fur Naturforschung - Section C Journal of Biosciences |
| Volume | 62 |
| Issue number | 1-2 |
| DOIs | |
| Publication status | Published - Jan 1 2007 |
Keywords
- Anisaldehyde
- B16-F10 melanoma cells
- Tyrosinase
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
Fingerprint Dive into the research topics of 'Anisaldehyde, a melanogenesis potentiator'. Together they form a unique fingerprint.
Cite this
Nitoda, T., Fan, M. D., & Kubo, I. (2007). Anisaldehyde, a melanogenesis potentiator. Zeitschrift fur Naturforschung - Section C Journal of Biosciences, 62(1-2), 143-149. https://doi.org/10.1515/znc-2007-1-224