Anaplastic thyroid carcinoma associated with granulocyte colony-stimulating factor: Report of a case

Takeo Fujita, Yutaka Ogasawara, Minoru Naito, Hiroyoshi Doihara, Nobuyoshi Shimizu

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

A 75-year-old woman was hospitalized due to a right axillary mass. She had undergone a resection of thyroid carcinoma 13 years earlier, followed by two subsequent operations for recurrent thyroid disease. A physical examination revealed a right axillary mass associated with skin ulceration. Persistent bleeding was observed at the skin ulcer associated with the right axillary lymph node, despite conservative treatment for the lesion. Surgery was thus performed to control persistent bleeding from the axillary ulcer, and a histopathological examination resulted in a diagnosis of poorly differentiated thyroid carcinoma. The postoperative course was uneventful, but marked leukocytosis and extensive skin metastases were recognized 30 days postoperatively. A systemic examination revealed no other lesions associated with marked leukocytosis, but elevated levels of granulocyte colony-stimulating factor were noted in a blood examination. As a result, her general condition deteriorated rapidly and the patient died 2 weeks after the onset of leukocytosis.

Original languageEnglish
Pages (from-to)63-67
Number of pages5
JournalSurgery Today
Volume36
Issue number1
DOIs
Publication statusPublished - Jan 2006

Fingerprint

Leukocytosis
Granulocyte Colony-Stimulating Factor
Thyroid Neoplasms
Hemorrhage
Skin Ulcer
Skin
Thyroid Diseases
Physical Examination
Ulcer
Lymph Nodes
Neoplasm Metastasis
Anaplastic Thyroid Carcinoma

Keywords

  • Granulocyte colony-stimulating factor
  • Leukocytosis
  • Thyroid cancer

ASJC Scopus subject areas

  • Surgery

Cite this

Anaplastic thyroid carcinoma associated with granulocyte colony-stimulating factor : Report of a case. / Fujita, Takeo; Ogasawara, Yutaka; Naito, Minoru; Doihara, Hiroyoshi; Shimizu, Nobuyoshi.

In: Surgery Today, Vol. 36, No. 1, 01.2006, p. 63-67.

Research output: Contribution to journalArticle

Fujita, Takeo ; Ogasawara, Yutaka ; Naito, Minoru ; Doihara, Hiroyoshi ; Shimizu, Nobuyoshi. / Anaplastic thyroid carcinoma associated with granulocyte colony-stimulating factor : Report of a case. In: Surgery Today. 2006 ; Vol. 36, No. 1. pp. 63-67.
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