Analysis of thrombosis on postoperative day 5 or later after microvascular reconstruction for head and neck cancers

Hideki Kadota, Minoru Sakuraba, Yoshihiro Kimata, Tomoyuki Yano, Ryuichi Hayashi

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Background. Because of the low incidence of late thrombosis in free flaps used for head and neck reconstruction, the risk factors, prognosis, and the optimal method of treatment are unclear. Methods. The timing of thrombosis, types of flaps, occluded vessels, causative factors, previous irradiation, and salvage rates were reviewed and compared between 79 patients who had thrombosis on postoperative day 4 or earlier (early-thrombosis group) and 24 patients who had thrombosis on postoperative day 5 or later (late-thrombosis group). Results. The main causative factor for thrombosis in the late-thrombosis group was wound infection (54%), whereas wound infection was present in only 1% of cases of thrombosis in the early-thrombosis group. None of the flaps could be salvaged in the late-thrombosis group. Conclusion. Poor salvage rate in the late-thrombosis group is the most serious problem. Prevention, early detection, and appropriate management of wound infection are essential for avoiding late thrombosis.

Original languageEnglish
Pages (from-to)635-641
Number of pages7
JournalHead and Neck
Volume31
Issue number5
DOIs
Publication statusPublished - May 2009

Keywords

  • Flap salvage
  • Head and neck cancer
  • Late thrombosis
  • Microvascular reconstruction
  • Wound infection

ASJC Scopus subject areas

  • Otorhinolaryngology

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