Analysis of signaling pathways activated by CCN proteins

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

CCN family proteins activate multiple intracellular phosphorylated kinase cascades to yield the multiple physiological functions of a variety of target cells. In this chapter, we describe our protocol examining the effects of these proteins on signal transduction pathways, especially mitogen-activated protein kinase cascades, activated by CCN member proteins, which examinations have been carried out mainly by using Western blotting methodologies.

Original languageEnglish
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc.
Pages139-143
Number of pages5
DOIs
Publication statusPublished - 2017

Publication series

NameMethods in Molecular Biology
Volume1489
ISSN (Print)1064-3745

Keywords

  • CCN signaling
  • ERK1/2 (p44/42 MAPK)
  • JNK
  • MAPK pathway
  • PI3K-PKB/Akt pathway
  • Western blotting
  • p38 MAPK

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

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