Analysis of risk factors for colonic diverticular bleeding: a matched case-control study

Yuusaku Sugihara, Shin Ei Kudo, Hideyuki Miyachi, Masashi Misawa, Shogo Okoshi, Hiroyuki Okada, Kazuhide Yamamoto

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Background/Aims: Diverticular bleeding can occasionally cause massive bleeding that requires urgent colonoscopy (CS) and treatment. The aim of this study was to identify significant risk factors for colonic diverticular hemorrhage. Methods: Between January 2009 and December 2012, 26,602 patients underwent CS at our institution. One hundred twenty-three patients underwent an urgent CS due to acute lower gastrointestinal hemorrhage. Seventy-two patients were diagnosed with colonic diverticular hemorrhage. One hundred forty-nine age- and sex-matched controls were selected from the patients with nonbleeding diverticula who underwent CS during the same period. The relationship of risk factors to diverticular bleeding was compared between the cases and controls. Results: Uni- and multivariate conditional logistic regression analyses demonstrated that the use of nonsteroidal anti-inflammatory drugs (odds ratio [OR], 14.70; 95% confidence interval [CI], 3.89 to 55.80; p

Original languageEnglish
Pages (from-to)244-249
Number of pages6
JournalGut and Liver
Volume10
Issue number2
DOIs
Publication statusPublished - Mar 1 2016

Fingerprint

Case-Control Studies
Colonoscopy
Hemorrhage
Gastrointestinal Hemorrhage
Diverticulum
Anti-Inflammatory Agents
Logistic Models
Odds Ratio
Regression Analysis
Confidence Intervals
Pharmaceutical Preparations
Therapeutics

Keywords

  • Anti-inflammatory agents
  • Cerebrovascular disease
  • Colonoscopy
  • Diverticular bleeding
  • Hyperuricemia
  • Non-steroidal

ASJC Scopus subject areas

  • Gastroenterology
  • Hepatology

Cite this

Sugihara, Y., Kudo, S. E., Miyachi, H., Misawa, M., Okoshi, S., Okada, H., & Yamamoto, K. (2016). Analysis of risk factors for colonic diverticular bleeding: a matched case-control study. Gut and Liver, 10(2), 244-249. https://doi.org/10.5009/gnl14407

Analysis of risk factors for colonic diverticular bleeding : a matched case-control study. / Sugihara, Yuusaku; Kudo, Shin Ei; Miyachi, Hideyuki; Misawa, Masashi; Okoshi, Shogo; Okada, Hiroyuki; Yamamoto, Kazuhide.

In: Gut and Liver, Vol. 10, No. 2, 01.03.2016, p. 244-249.

Research output: Contribution to journalArticle

Sugihara, Y, Kudo, SE, Miyachi, H, Misawa, M, Okoshi, S, Okada, H & Yamamoto, K 2016, 'Analysis of risk factors for colonic diverticular bleeding: a matched case-control study', Gut and Liver, vol. 10, no. 2, pp. 244-249. https://doi.org/10.5009/gnl14407
Sugihara, Yuusaku ; Kudo, Shin Ei ; Miyachi, Hideyuki ; Misawa, Masashi ; Okoshi, Shogo ; Okada, Hiroyuki ; Yamamoto, Kazuhide. / Analysis of risk factors for colonic diverticular bleeding : a matched case-control study. In: Gut and Liver. 2016 ; Vol. 10, No. 2. pp. 244-249.
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