Analysis of mental health status and stress factors affecting clinical research coordinators

Shihoko Namba, Yasuhiro Kawakami, Shigeki Nishihara, Toshiaki Sendo

Research output: Contribution to journalArticlepeer-review


The work of clinical research coordinators (CRCs) is extremely important and requires both interpersonal skills and high expertise. While the work is rewarding, it can also produce significant tension and burden. The stress felt by CRCs has not been reliably investigated in previous studies, and stress scales specific for this occupational category do not exist Therefore, we designed a tool for CRC stress measurement (CRC stress management scale) to better discern the mental health status of CRCs and to standardize the measurement of stress levels in this group. In this study, the stress scale, an attribute investigation form, and the Japanese version of self-rating depression scale (SDS) were distributed to participating CRCs, and 288 responses were obtained (representing a 57.6% recovery rate). Five factors were extracted from the newly created 50-item stress scale by exploratory factor analysis. All the identified factors had a of 0.75 and above. The questions constituting each factor displayed a reasonable internal consistency. Furthermore, scores on the CRC stress scale and the Japanese version of SDS showed a positive correlation. In conclusion, the CRC stress management scale was found to be useful for the analysis of mental health specifically related to CRCs.

Original languageEnglish
Pages (from-to)37-46
Number of pages10
JournalJapanese Journal of Clinical Pharmacology and Therapeutics
Issue number1
Publication statusPublished - Jan 2013


  • Clinical research coordinator
  • Factor analysis
  • Self-rating depression scale
  • Stress

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)


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