Analysis of DNA damage generated by high-energy particles.

Hiroaki Terato, Ruri Tanaka, Yusuke Nakaarai, Yoshiya Furusawa, Hiroshi Ide

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Ionizing radiation generates isolated and localized multiple (i.e., clustered) lesions in DNA, and the latter is believed to be primarily responsible for deleterious biological consequences such as cell killing and mutations. In the present study, we irradiated plasmid and lambda DNA by ionizing radiations with different linear energy transfer (LET) values, and compared the yields of isolated and clustered DNA lesions.

Original languageEnglish
Pages (from-to)145-146
Number of pages2
JournalNucleic acids symposium series (2004)
Issue number48
Publication statusPublished - 2004
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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