An improved protocol for Petasis reaction of 2-pyridinecarbaldehydes

Hiroki Mandai, Kyouta Murota, Takashi Sakai

Research output: Contribution to journalArticlepeer-review

17 Citations (Scopus)


A highly efficient and improved method has been developed for Petasis reactions of various 2-pyridinecarbaldehydes with secondary amines and boronic acids under catalyst-free conditions. The desired products are obtained in up to 96% yield in refluxed acetonitrile.

Original languageEnglish
Pages (from-to)4779-4782
Number of pages4
JournalTetrahedron Letters
Issue number36
Publication statusPublished - Sep 8 2010

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


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