An epidemiologic research design using the annual of the pathological autopsy cases in Japan

Toshihide Tsuda, E. Yamamoto, A. Babazono, Y. Mino, T. Ogawa, J. Shigemi, H. Aoyama

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Epidemiologic research designs using the Annual of the Pathological Autopsy Cases in Japan (APAC hereinafter) are discussed in this paper. The APAC data base has been recommended for use in epidemiologic research. However, it has not often been utilized for such research, even though it covers all pathological autopsy cases in Japan, perhaps because of different sampling proportions of each disease and because of the dead control series in APAC. First, we present epidemiologic measures in using the APAC. We show that the data base can be treated as a case-control design and that the magnitude of the exposure effect should be estimated by an odds ratio. Next, selection bias and information bias in using the APAC are discussed. The independence of the control series from the exposure is important in the determination of the control disease. Because this design is based on internal comparison, non-differential misclassification should be stressed more than differential misclassification.

Original languageEnglish
Pages (from-to)753-761
Number of pages9
JournalJapanese Journal of Hygiene
Volume49
Issue number4
Publication statusPublished - 1994

Fingerprint

Epidemiologic Research Design
Autopsy
Japan
Databases
Selection Bias
Research
Odds Ratio

Keywords

  • case-control study
  • epidemiology
  • Odds ratio
  • PMR
  • the Annual of the Pathological Autopsy Cases in Japan

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

Cite this

Tsuda, T., Yamamoto, E., Babazono, A., Mino, Y., Ogawa, T., Shigemi, J., & Aoyama, H. (1994). An epidemiologic research design using the annual of the pathological autopsy cases in Japan. Japanese Journal of Hygiene, 49(4), 753-761.

An epidemiologic research design using the annual of the pathological autopsy cases in Japan. / Tsuda, Toshihide; Yamamoto, E.; Babazono, A.; Mino, Y.; Ogawa, T.; Shigemi, J.; Aoyama, H.

In: Japanese Journal of Hygiene, Vol. 49, No. 4, 1994, p. 753-761.

Research output: Contribution to journalArticle

Tsuda, T, Yamamoto, E, Babazono, A, Mino, Y, Ogawa, T, Shigemi, J & Aoyama, H 1994, 'An epidemiologic research design using the annual of the pathological autopsy cases in Japan', Japanese Journal of Hygiene, vol. 49, no. 4, pp. 753-761.
Tsuda, Toshihide ; Yamamoto, E. ; Babazono, A. ; Mino, Y. ; Ogawa, T. ; Shigemi, J. ; Aoyama, H. / An epidemiologic research design using the annual of the pathological autopsy cases in Japan. In: Japanese Journal of Hygiene. 1994 ; Vol. 49, No. 4. pp. 753-761.
@article{8a8ce40a6512424e822215eaff0c5d0d,
title = "An epidemiologic research design using the annual of the pathological autopsy cases in Japan",
abstract = "Epidemiologic research designs using the Annual of the Pathological Autopsy Cases in Japan (APAC hereinafter) are discussed in this paper. The APAC data base has been recommended for use in epidemiologic research. However, it has not often been utilized for such research, even though it covers all pathological autopsy cases in Japan, perhaps because of different sampling proportions of each disease and because of the dead control series in APAC. First, we present epidemiologic measures in using the APAC. We show that the data base can be treated as a case-control design and that the magnitude of the exposure effect should be estimated by an odds ratio. Next, selection bias and information bias in using the APAC are discussed. The independence of the control series from the exposure is important in the determination of the control disease. Because this design is based on internal comparison, non-differential misclassification should be stressed more than differential misclassification.",
keywords = "case-control study, epidemiology, Odds ratio, PMR, the Annual of the Pathological Autopsy Cases in Japan",
author = "Toshihide Tsuda and E. Yamamoto and A. Babazono and Y. Mino and T. Ogawa and J. Shigemi and H. Aoyama",
year = "1994",
language = "English",
volume = "49",
pages = "753--761",
journal = "Japanese Journal of Hygiene",
issn = "0021-5082",
publisher = "Japanese Society for Hygiene",
number = "4",

}

TY - JOUR

T1 - An epidemiologic research design using the annual of the pathological autopsy cases in Japan

AU - Tsuda, Toshihide

AU - Yamamoto, E.

AU - Babazono, A.

AU - Mino, Y.

AU - Ogawa, T.

AU - Shigemi, J.

AU - Aoyama, H.

PY - 1994

Y1 - 1994

N2 - Epidemiologic research designs using the Annual of the Pathological Autopsy Cases in Japan (APAC hereinafter) are discussed in this paper. The APAC data base has been recommended for use in epidemiologic research. However, it has not often been utilized for such research, even though it covers all pathological autopsy cases in Japan, perhaps because of different sampling proportions of each disease and because of the dead control series in APAC. First, we present epidemiologic measures in using the APAC. We show that the data base can be treated as a case-control design and that the magnitude of the exposure effect should be estimated by an odds ratio. Next, selection bias and information bias in using the APAC are discussed. The independence of the control series from the exposure is important in the determination of the control disease. Because this design is based on internal comparison, non-differential misclassification should be stressed more than differential misclassification.

AB - Epidemiologic research designs using the Annual of the Pathological Autopsy Cases in Japan (APAC hereinafter) are discussed in this paper. The APAC data base has been recommended for use in epidemiologic research. However, it has not often been utilized for such research, even though it covers all pathological autopsy cases in Japan, perhaps because of different sampling proportions of each disease and because of the dead control series in APAC. First, we present epidemiologic measures in using the APAC. We show that the data base can be treated as a case-control design and that the magnitude of the exposure effect should be estimated by an odds ratio. Next, selection bias and information bias in using the APAC are discussed. The independence of the control series from the exposure is important in the determination of the control disease. Because this design is based on internal comparison, non-differential misclassification should be stressed more than differential misclassification.

KW - case-control study

KW - epidemiology

KW - Odds ratio

KW - PMR

KW - the Annual of the Pathological Autopsy Cases in Japan

UR - http://www.scopus.com/inward/record.url?scp=0028132049&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028132049&partnerID=8YFLogxK

M3 - Article

VL - 49

SP - 753

EP - 761

JO - Japanese Journal of Hygiene

JF - Japanese Journal of Hygiene

SN - 0021-5082

IS - 4

ER -