Abstract
The present review focuses an early history of Japanese amyotrophic lateral sclerosis (ALS)-related diseases and the current development. In relation to foreign previous reports, five topics are introduced and discussed on ALS with dementia, ALS/Parkinsonism dementia complex (ALS/PDC), familial ALS (FALS), spinal bulbar muscular atrophy (SBMA), and multisystem involvement especially in cerebellar system of ALS including ALS/SCA (spinocerebellar ataxia) crossroad mutation Asidan. This review found the great contribution of Japanese reports on the above five topics, and confirmed the great development of ALS-related diseases over the past 120 years.
Original language | English |
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Pages (from-to) | 141-165 |
Number of pages | 25 |
Journal | Clinical Neurology |
Volume | 58 |
Issue number | 3 |
DOIs | |
Publication status | Published - 2018 |
Keywords
- ALS
- ALS/PDC
- Asidan
- FALS
- SBMA
ASJC Scopus subject areas
- Clinical Neurology