An early history of CCN2/CTGF research: the road to CCN2 via hcs24, ctgf, ecogenin, and regenerin

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Abstract

The principal aim of this historical review is to present the processes by which the different aspects of CCN2/CTGF/Hcs24 were discovered by different groups and how much CCN2/CTGF, by being integrated into CCN family, has contributed to the establishment of the basic concepts regarding the role and functions of this new class of proteins. This review should be particularly useful to new investigators who have recently entered this exciting field of study and also provides a good opportunity to acknowledge the input of those individuals who participated in the development of this scientific field.

Original languageEnglish
Pages (from-to)1-12
Number of pages12
JournalJournal of Cell Communication and Signaling
DOIs
Publication statusAccepted/In press - Oct 26 2017

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Keywords

  • CCN family
  • CCN proteins
  • CCN2/CTGF/Hcs24
  • Ecogenin
  • Regenerin

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Cell Biology

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