Abstract
A 40-year-old man suffering from right cheek swelling was first diagnosed with ameloblastoma or anaplastic poorly-differentiated carcinoma of the head and neck region. He received 2 courses of CDDP/TXT chemotherapy (cisplatin 75 mg/m2, docetaxel 80 mg/m2) and achieved a partial response, but his carcinoma of the pancreas recurred. He also achieved a partial response with 2 courses of CBDCA/TXL regimen (carboplatin AUC=6, paclitaxel 200 mg/m2), but later died from his progressive disease. The autopsy revealed a pathological diagnosis of metastatic endocrine carcinoma of the pancreas. This case was close to a cancer with an unknown primary (CUP) site, and several favorable sub-sets of CUP have been identified, which are responsive to systemic chemotherapy. Poorly-differentiated neuroendocrine carcinomas like this case are highly sensitive to chemotherapy, and a careful pathological diagnosis may clarify its sensitivity to chemotherapy and the prognosis.
| Original language | English |
|---|---|
| Pages (from-to) | 671-673 |
| Number of pages | 3 |
| Journal | Gan to kagaku ryoho. Cancer & chemotherapy |
| Volume | 32 |
| Issue number | 5 |
| Publication status | Published - May 2005 |
| Externally published | Yes |
Fingerprint
ASJC Scopus subject areas
- Cancer Research
- Pharmacology
Cite this
An autopsied case of metastatic endocrine carcinoma of the pancreas with primary site difficult to identify. / Nishimori, Hisakazu; Takahashi, Shunji; Nagasaki, Eijiro; Kobayashi, Takayuki; Yokoyama, Masahiro; Shinozaki, Eiji; Mishima, Yuko; Terui, Yasuhito; Chin, Keisyo; Mizunuma, Nobuyuki; Ito, Yoshinori; Inamura, Kentaro; Hatake, Kiyohiko.
In: Gan to kagaku ryoho. Cancer & chemotherapy, Vol. 32, No. 5, 05.2005, p. 671-673.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - An autopsied case of metastatic endocrine carcinoma of the pancreas with primary site difficult to identify
AU - Nishimori, Hisakazu
AU - Takahashi, Shunji
AU - Nagasaki, Eijiro
AU - Kobayashi, Takayuki
AU - Yokoyama, Masahiro
AU - Shinozaki, Eiji
AU - Mishima, Yuko
AU - Terui, Yasuhito
AU - Chin, Keisyo
AU - Mizunuma, Nobuyuki
AU - Ito, Yoshinori
AU - Inamura, Kentaro
AU - Hatake, Kiyohiko
PY - 2005/5
Y1 - 2005/5
N2 - A 40-year-old man suffering from right cheek swelling was first diagnosed with ameloblastoma or anaplastic poorly-differentiated carcinoma of the head and neck region. He received 2 courses of CDDP/TXT chemotherapy (cisplatin 75 mg/m2, docetaxel 80 mg/m2) and achieved a partial response, but his carcinoma of the pancreas recurred. He also achieved a partial response with 2 courses of CBDCA/TXL regimen (carboplatin AUC=6, paclitaxel 200 mg/m2), but later died from his progressive disease. The autopsy revealed a pathological diagnosis of metastatic endocrine carcinoma of the pancreas. This case was close to a cancer with an unknown primary (CUP) site, and several favorable sub-sets of CUP have been identified, which are responsive to systemic chemotherapy. Poorly-differentiated neuroendocrine carcinomas like this case are highly sensitive to chemotherapy, and a careful pathological diagnosis may clarify its sensitivity to chemotherapy and the prognosis.
AB - A 40-year-old man suffering from right cheek swelling was first diagnosed with ameloblastoma or anaplastic poorly-differentiated carcinoma of the head and neck region. He received 2 courses of CDDP/TXT chemotherapy (cisplatin 75 mg/m2, docetaxel 80 mg/m2) and achieved a partial response, but his carcinoma of the pancreas recurred. He also achieved a partial response with 2 courses of CBDCA/TXL regimen (carboplatin AUC=6, paclitaxel 200 mg/m2), but later died from his progressive disease. The autopsy revealed a pathological diagnosis of metastatic endocrine carcinoma of the pancreas. This case was close to a cancer with an unknown primary (CUP) site, and several favorable sub-sets of CUP have been identified, which are responsive to systemic chemotherapy. Poorly-differentiated neuroendocrine carcinomas like this case are highly sensitive to chemotherapy, and a careful pathological diagnosis may clarify its sensitivity to chemotherapy and the prognosis.
UR - http://www.scopus.com/inward/record.url?scp=19544374527&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=19544374527&partnerID=8YFLogxK
M3 - Article
C2 - 15918570
AN - SCOPUS:19544374527
VL - 32
SP - 671
EP - 673
JO - Japanese Journal of Cancer and Chemotherapy
JF - Japanese Journal of Cancer and Chemotherapy
SN - 0385-0684
IS - 5
ER -