An association between Helicobacter pylori and upper respiratory tract disease: Fact or fiction?

Shin Kariya, Mitsuhiro Okano, Kazunori Nishizaki

Research output: Contribution to journalArticlepeer-review

26 Citations (Scopus)

Abstract

Helicobacter pylori (H. pylori) is a major cause of chronic gastritis and gastric ulcers and considerable evidence supports the notion that infection with this bacterium is also associated with gastric malignancy in addition to various other conditions including pulmonary, vascular and autoimmune disorders. Gastric juice infected with H. pylori might play an important role in upper respiratory tract infection. Although direct and/or indirect mechanisms might be involved in the association between H. pylori and upper respiratory tract diseases, the etiological role of H. pylori in upper respiratory tract disorders has not yet been fully elucidated. Although various studies over the past two decades have suggested a relationship between H. pylori and upper respiratory tract diseases, the findings are inconsistent. The present overview describes the outcomes of recent investigations into the impact of H. pylori on upper respiratory tract and adjacent lesions.

Original languageEnglish
Pages (from-to)1470-1484
Number of pages15
JournalWorld journal of gastroenterology
Volume20
Issue number6
DOIs
Publication statusPublished - Feb 14 2014

Keywords

  • Adenoid
  • Cancer
  • Ear
  • Larynx
  • Oral cavity
  • Paranasal sinus
  • Pharynx
  • Upper respiratory tract

ASJC Scopus subject areas

  • Gastroenterology

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